Gene Symbol | ESPN |
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Entrez Gene | 83715 |
Alt Symbol | DFNB36, LP2654 |
Species | Human |
Gene Type | protein-coding |
Description | espin |
Other Description | autosomal recessive deafness type 36 protein|ectoplasmic specialization protein |
Swissprots | B1AK53 Q6XYB2 Q9Y329 Q9H0A2 |
Accessions | B1AK53 CAI22151 CAI22163 EAW71535 EAW71536 EAW71537 EAW71538 AF134401 AAD24480 AL136880 CAB66814 AL834172 CAD38870 AY203958 AAP34481 BC156375 AAI56376 BC172457 AAI72457 BM713713 XM_005263501 XP_005263558 XM_011542231 XP_011540533 XM_011542232 XP_011540534 XM_011542233 XP_011540535 XM_011542234 XP_011540536 XM_011542235 XP_011540537 XM_011542236 XP_011540538 XM_011542237 XP_011540539 XM_011542238 XP_011540540 XR_946774 XR_946775 NM_031475 NP_113663 |
Function | Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, stereocilium {ECO:0000250}. Cell projection, microvillus {ECO:0000250}. |
Espin CRISPR/Cas9 KO Plasmid (h) - sc-403106 from Santa Cruz Biotechnology
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Espin HDR Plasmid (h) - sc-403106-HDR from Santa Cruz Biotechnology
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Espin Double Nickase Plasmid (h) - sc-403106-NIC from Santa Cruz Biotechnology
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Espin Double Nickase Plasmid (h2) - sc-403106-NIC-2 from Santa Cruz Biotechnology
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Espin CRISPR Activation Plasmid (h) - sc-403106-ACT from Santa Cruz Biotechnology
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Espin CRISPR Activation Plasmid (h2) - sc-403106-ACT-2 from Santa Cruz Biotechnology
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Espin Lentiviral Activation Particles (h) - sc-403106-LAC from Santa Cruz Biotechnology
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Espin Lentiviral Activation Particles (h2) - sc-403106-LAC-2 from Santa Cruz Biotechnology
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Espin siRNA (h) - sc-78697 from Santa Cruz Biotechnology
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Espin shRNA Plasmid (h) - sc-78697-SH from Santa Cruz Biotechnology
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Espin shRNA (h) Lentiviral Particles - sc-78697-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU149121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7988 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7988 from Sigma-Aldrich
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ESPN siRNA (Human) - CRJ3175 from Cohesion Biosciences
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ESPN - MBS8215621 from MyBioSource
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Espin CRISPR/Cas9 KO Plasmid (h2) - sc-403106-KO-2 from Santa Cruz Biotechnology
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Espin HDR Plasmid (h2) - sc-403106-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ESPN(NM_031475.2) - SHH039411 from Creative biogene
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Human ESPN siRNA - orb273676 from Biorbyt
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ESPN shRNA Plasmid (Human) - CHJ3175 from Cohesion Biosciences
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ESPN miRNA 3'UTR clone - MiUTR1H-03312 from Creative biogene
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