Gene Symbol | ARSI |
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Entrez Gene | 340075 |
Alt Symbol | SPG66 |
Species | Human |
Gene Type | protein-coding |
Description | arylsulfatase family, member I |
Other Description | ASI|arylsulfatase I |
Swissprots | A1L3B0 B7XD03 B3KV22 Q5FYB1 |
Accessions | CAH25968 EAW61740 Q5FYB1 AB448735 BAH11166 AK122641 BAG53634 AY875937 AAW66665 BC111002 BC129995 AAI29996 BC129996 AAI29997 CN369733 DA264664 DA759270 NM_001012301 NP_001012301 |
Function | Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. {ECO:0000269|PubMed:16500042, ECO:0000269|PubMed:19262745}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19262745}. Endoplasmic reticulum {ECO:0000269|PubMed:19262745}. Note=Localized in the intracellular granular structures. |
Tissue Specificity | Expressed in placenta, in embryonic stem cells, fetal eyes and lens. {ECO:0000269|PubMed:16500042, ECO:0000269|PubMed:19262745}. |
Arylsulfatase I CRISPR/Cas9 KO Plasmid (h) - sc-410423 from Santa Cruz Biotechnology
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Arylsulfatase I HDR Plasmid (h) - sc-410423-HDR from Santa Cruz Biotechnology
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Arylsulfatase I Double Nickase Plasmid (h) - sc-410423-NIC from Santa Cruz Biotechnology
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Arylsulfatase I Double Nickase Plasmid (h2) - sc-410423-NIC-2 from Santa Cruz Biotechnology
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Arylsulfatase I CRISPR Activation Plasmid (h) - sc-410423-ACT from Santa Cruz Biotechnology
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Arylsulfatase I CRISPR Activation Plasmid (h2) - sc-410423-ACT-2 from Santa Cruz Biotechnology
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Arylsulfatase I Lentiviral Activation Particles (h) - sc-410423-LAC from Santa Cruz Biotechnology
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Arylsulfatase I Lentiviral Activation Particles (h2) - sc-410423-LAC-2 from Santa Cruz Biotechnology
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Arylsulfatase I siRNA (h) - sc-91640 from Santa Cruz Biotechnology
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Arylsulfatase I shRNA Plasmid (h) - sc-91640-SH from Santa Cruz Biotechnology
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Arylsulfatase I shRNA (h) Lentiviral Particles - sc-91640-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU156991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3546 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3546 from Sigma-Aldrich
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ARSI siRNA (Human) - CRJ7325 from Cohesion Biosciences
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ARSI - MBS8236114 from MyBioSource
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shRNA set against Human ARSI (NM_001012301.2) - SHH240890 from Creative biogene
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Human ARSI siRNA - orb277826 from Biorbyt
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ARSI shRNA Plasmid (Human) - CHJ7325 from Cohesion Biosciences
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ARSI miRNA 3'UTR clone - MiUTR3H-10963 from Creative biogene
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