Gene Symbol | ENO2 |
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Entrez Gene | 2026 |
Alt Symbol | HEL-S-279, NSE |
Species | Human |
Gene Type | protein-coding |
Description | enolase 2 (gamma, neuronal) |
Other Description | 2-phospho-D-glycerate hydro-lyase|2-phospho-D-glycerate hydrolyase|epididymis secretory protein Li 279|gamma-enolase|neural enolase|neuron specific gamma enolase|neuron-specific enolase|neurone-specific enolase |
Swissprots | P09104 Q96J33 B7Z2X9 |
Accessions | AAB51320 CAA36215 CBN61368 EAW88709 EAW88710 EAW88711 P09104 AK124656 BAG54062 AK290525 BAF83214 AK295220 BAH12015 AK312402 BAG35316 BC002745 AAH02745 BT007383 AAP36047 CR536582 CAG38819 DQ893819 ABM84745 EU176168 ABW03619 EU794607 ACJ13661 M22349 AAB59554 M36768 AAA52388 X13120 CAA31512 X14327 CAA32505 Y00691 NM_001975 NP_001966 |
Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. {ECO:0000250}. |
Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
Top Pathways | Glycolysis / Gluconeogenesis, RNA degradation, Biosynthesis of amino acids, Carbon metabolism |
Active human NSE full length protein - ab168023 from Abcam
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Human NSE full length protein - ab78797 from Abcam
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Human NSE peptide - ab99878 from Abcam
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Human NSE protein fragment - ab53387 from Abcam
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ENO2 / NSE Antibody Blocking Peptide - LS-E7092 from LifeSpan Bioscience
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ENO2 / NSE Antibody Blocking Peptide - LS-E7093 from LifeSpan Bioscience
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ENO2 / NSE Antibody Blocking Peptide - LS-E22240 from LifeSpan Bioscience
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ENO2 / NSE Antibody Blocking Peptide - LS-E22241 from LifeSpan Bioscience
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ENO2 / NSE Antibody Blocking Peptide - LS-E7431 from LifeSpan Bioscience
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Enolase 2/Neuron-specific Enolase Recombinant Protein - H00002026-P02 from Novus Biologicals
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Enolase 2/Neuron-specific Enolase Recombinant Protein - H00002026-P01 from Novus Biologicals
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Enolase 2/Neuron-specific Enolase Partial Recombinant Protein - H00002026-Q01 from Novus Biologicals
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Recombinant Human Enolase 2/Neuron-specific Enolase Protein - NBC1-18342 from Novus Biologicals
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ENO2-Antibody-Center-Blocking-Peptide - BP18121c from Abgent, a WuXi AppTec company
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NSE-Antibody-Y25-Blocking-Peptide - BP2780b from Abgent, a WuXi AppTec company
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NSE-Antibody-Y236-Blocking-Peptide - BP2780a from Abgent, a WuXi AppTec company
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Phospho-NSEY25-Antibody-Blocking-peptide - BP3727a from Abgent, a WuXi AppTec company
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Phospho-NSEY236-Antibody-Blocking-peptide - BP3589a from Abgent, a WuXi AppTec company
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Recombinant human Gamma-enolase (OPCA00838) - OPCA00838 from Aviva Systems Biology
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NSE, Recombinant (OPMA00027) - OPMA00027 from Aviva Systems Biology
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Neuron Specific Enolase Protein (OPMA04327) - OPMA04327 from Aviva Systems Biology
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ENO2 Protein (OPPA00819) - OPPA00819 from Aviva Systems Biology
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ENO2 Protein (OPPA01688) - OPPA01688 from Aviva Systems Biology
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ENO2 Protein (OPPA01798) - OPPA01798 from Aviva Systems Biology
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Human ENO2 protein (His Tag) - orb138752 from Biorbyt
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