| Gene Symbol |
TINAGL1
|
| Entrez Gene |
64129
|
| Alt Symbol |
ARG1, LCN7, LIECG3, TINAGRP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulointerstitial nephritis antigen-like 1
|
| Other Description |
OLRG-2|P3ECSL|TIN Ag-related protein|TIN-Ag-RP|TINAG-like 1|androgen-regulated gene 1|glucocorticoid-inducible protein 5|lipocalin 7|oxidized-LDL responsive gene 2|tubulointerstitial nephritis antigen-like|tubulointerstitial nephritis antigen-related protein
|
| Swissprots |
Q96JW3 D3DPN8 Q9GZM7 Q96GZ4 A8K9Q5 Q8WZ23 Q8TEJ9 B4DPK6
|
| Accessions |
AAG40154 BAB18727 CAI72096 EAX07603 EAX07604 EAX07605 EAX07606 EAX07607 Q9GZM7 AB050716 BAB18636 AF205436 AAG33699 AF236150 AAG38876 AF289569 AAL55753 AK027839 BAB55403 AK074124 BAB84950 AK075398 BAC11596 AK292770 BAF85459 AK296322 BAG59016 AK298038 BAG60337 AK298382 BAG60618 AK301070 BAG62677 AY358421 AAQ88787 BC009048 AAH09048 BC064633 AAH64633 BM923842 DA656570 XM_005271106 XP_005271163 XM_005271107 XP_005271164 XM_011541946 XP_011540248 NM_001204414 NP_001191343 NM_001204415 NP_001191344 NM_022164 NP_071447
|
| Function |
May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:10799322, ECO:0000269|PubMed:11170462}.
|
| Tissue Specificity |
Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle cells, but also in cardiac and skeletal muscle cells as well as kidney. {ECO:0000269|PubMed:11170462}.
|