Gene Symbol | INTS5 |
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Entrez Gene | 80789 |
Alt Symbol | INT5, KIAA1698 |
Species | Human |
Gene Type | protein-coding |
Description | integrator complex subunit 5 |
Other Description | - |
Swissprots | Q9C0G5 Q8N6W5 Q6P9B9 |
Accessions | EAW74051 Q6P9B9 AB051485 BAB21789 AK074261 AK123587 BC028025 AAH28025 BC060841 AAH60841 BK005724 DAA05724 NM_030628 NP_085131 |
Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
Subcellular Location | Nucleus. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
INTS5 CRISPR/Cas9 KO Plasmid (h) - sc-410506 from Santa Cruz Biotechnology
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INTS5 HDR Plasmid (h) - sc-410506-HDR from Santa Cruz Biotechnology
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INTS5 Double Nickase Plasmid (h) - sc-410506-NIC from Santa Cruz Biotechnology
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INTS5 Double Nickase Plasmid (h2) - sc-410506-NIC-2 from Santa Cruz Biotechnology
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INTS5 CRISPR Activation Plasmid (h) - sc-410506-ACT from Santa Cruz Biotechnology
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INTS5 CRISPR Activation Plasmid (h2) - sc-410506-ACT-2 from Santa Cruz Biotechnology
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INTS5 Lentiviral Activation Particles (h) - sc-410506-LAC from Santa Cruz Biotechnology
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INTS5 Lentiviral Activation Particles (h2) - sc-410506-LAC-2 from Santa Cruz Biotechnology
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INTS5 siRNA (h) - sc-96918 from Santa Cruz Biotechnology
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INTS5 shRNA Plasmid (h) - sc-96918-SH from Santa Cruz Biotechnology
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INTS5 shRNA (h) Lentiviral Particles - sc-96918-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10717 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10717 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00409 from Sigma-Aldrich
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INTS5 siRNA (Human) - CRJ2916 from Cohesion Biosciences
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INTS5 - MBS8220371 from MyBioSource
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shRNA set against Human INTS5 (NM_030628.1) - SHH320005 from Creative biogene
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Human INTS5 siRNA - orb273417 from Biorbyt
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INTS5 shRNA Plasmid (Human) - CHJ2916 from Cohesion Biosciences
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INTS5 miRNA 3'UTR clone - MiUTR1H-04972 from Creative biogene
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