| Gene Symbol | ADH5 |
|---|---|
| Entrez Gene | 128 |
| Alt Symbol | ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR |
| Species | Human |
| Gene Type | protein-coding |
| Description | alcohol dehydrogenase 5 (class III), chi polypeptide |
| Other Description | S-(hydroxymethyl)glutathione dehydrogenase|alcohol dehydrogenase (class III), chi polypeptide|alcohol dehydrogenase class chi chain|alcohol dehydrogenase class-3|alcohol dehydrogenase class-III|formaldehyde dehydrogenase|glutathione-dependent formaldehyde dehydrogenase |
| Swissprots | P11766 Q6FHR2 |
| Accessions | AAA51596 AAA83432 AAX81412 EAX06084 EAX06085 EAX06086 P11766 AK124994 AK129570 AK312367 BAG35285 BC014665 AAH14665 BC070491 AAH70491 BQ881561 BT019832 AAV38635 BT019833 AAV38636 CR536491 CAG38730 CR541689 CAG46490 DA737788 M29872 AAA51597 M30471 AAA79018 NM_000671 NP_000662 |
| Function | Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Glycolysis / Gluconeogenesis, Chemical carcinogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism |