Gene Symbol | ADH5 |
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Entrez Gene | 128 |
Alt Symbol | ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR |
Species | Human |
Gene Type | protein-coding |
Description | alcohol dehydrogenase 5 (class III), chi polypeptide |
Other Description | S-(hydroxymethyl)glutathione dehydrogenase|alcohol dehydrogenase (class III), chi polypeptide|alcohol dehydrogenase class chi chain|alcohol dehydrogenase class-3|alcohol dehydrogenase class-III|formaldehyde dehydrogenase|glutathione-dependent formaldehyde dehydrogenase |
Swissprots | P11766 Q6FHR2 |
Accessions | AAA51596 AAA83432 AAX81412 EAX06084 EAX06085 EAX06086 P11766 AK124994 AK129570 AK312367 BAG35285 BC014665 AAH14665 BC070491 AAH70491 BQ881561 BT019832 AAV38635 BT019833 AAV38636 CR536491 CAG38730 CR541689 CAG46490 DA737788 M29872 AAA51597 M30471 AAA79018 NM_000671 NP_000662 |
Function | Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. |
Subcellular Location | Cytoplasm. |
Top Pathways | Glycolysis / Gluconeogenesis, Chemical carcinogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism |
ADH5 CRISPR/Cas9 KO Plasmid (h) - sc-403859 from Santa Cruz Biotechnology
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ADH5 HDR Plasmid (h) - sc-403859-HDR from Santa Cruz Biotechnology
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ADH5 Double Nickase Plasmid (h) - sc-403859-NIC from Santa Cruz Biotechnology
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ADH5 Double Nickase Plasmid (h2) - sc-403859-NIC-2 from Santa Cruz Biotechnology
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ADH5 CRISPR Activation Plasmid (h) - sc-403859-ACT from Santa Cruz Biotechnology
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ADH5 CRISPR Activation Plasmid (h2) - sc-403859-ACT-2 from Santa Cruz Biotechnology
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ADH5 Lentiviral Activation Particles (h) - sc-403859-LAC from Santa Cruz Biotechnology
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ADH5 Lentiviral Activation Particles (h2) - sc-403859-LAC-2 from Santa Cruz Biotechnology
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ADH5 siRNA (h) - sc-105044 from Santa Cruz Biotechnology
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ADH5 shRNA Plasmid (h) - sc-105044-SH from Santa Cruz Biotechnology
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ADH5 shRNA (h) Lentiviral Particles - sc-105044-V from Santa Cruz Biotechnology
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alcohol dehydrogenase 5 RNAi - H00000128-R01 from Novus Biologicals
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MISSION® esiRNA - EHU104681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2877 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2877 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09324 from Sigma-Aldrich
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ADH5 siRNA (Human) - CRH0088 from Cohesion Biosciences
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ADH5 - MBS8206345 from MyBioSource
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shRNA set against Human ADH5 (NM_000671.3) - SHH232374 from Creative biogene
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shRNA set against Human ADH5(NM_000671.3) - SHG042361 from Creative biogene
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Human ADH5 siRNA - orb260590 from Biorbyt
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ADH5 shRNA Plasmid (Human) - CHH0088 from Cohesion Biosciences
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ADH5 miRNA 3'UTR clone - MiUTR1H-00196 from Creative biogene
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