Gene Symbol | PDXK |
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Entrez Gene | 8566 |
Alt Symbol | C21orf124, C21orf97, HEL-S-1a, PKH, PNK, PRED79 |
Species | Human |
Gene Type | protein-coding |
Description | pyridoxal (pyridoxine, vitamin B6) kinase |
Other Description | epididymis secretory sperm binding protein Li 1a|pyridoxal kinase|pyridoxamine kinase|pyridoxine kinase|vitamin B6 kinase |
Swissprots | O00764 Q7Z2Y0 Q9BS02 |
Accessions | BAA95540 CBX51400 CDH61624 CDH93590 EAX09475 EAX09477 O00764 AB621819 BAK64155 AI131245 AI652877 AK024977 BAB15048 AK027018 AK056502 AK094630 AK225206 AL109793 AL110184 AL137632 AL161960 AL355712 AL355713 AW245602 AW245860 AY303972 AAP73047 BC000123 AAH00123 BC003651 BC005825 AAH05825 BC008008 AAH08008 BC021550 AAH21550 BC041020 AAH41020 BC063541 BE671761 BI871733 BQ653540 BU192292 CB989301 CX867421 DA116202 DA398180 DA736443 DA772127 DB010203 EU794642 ACJ13696 U89606 AAC51233 XM_005261195 XP_005261252 XM_005261196 XP_005261253 XM_005261198 XP_005261255 XM_005261199 XP_005261256 XM_011529758 XP_011528060 XM_011529759 XP_011528061 XM_011529760 XP_011528062 XM_011529761 XP_011528063 XM_011529762 XP_011528064 NM_003681 NP_003672 NM_021941 |
Function | Required for synthesis of pyridoxal-5-phosphate from vitamin B6. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa. |
Top Pathways | Vitamin B6 metabolism |
pyridoxal kinase CRISPR/Cas9 KO Plasmid (h) - sc-406685 from Santa Cruz Biotechnology
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pyridoxal kinase HDR Plasmid (h) - sc-406685-HDR from Santa Cruz Biotechnology
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pyridoxal kinase Double Nickase Plasmid (h) - sc-406685-NIC from Santa Cruz Biotechnology
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pyridoxal kinase Double Nickase Plasmid (h2) - sc-406685-NIC-2 from Santa Cruz Biotechnology
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pyridoxal kinase CRISPR Activation Plasmid (h) - sc-406685-ACT from Santa Cruz Biotechnology
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pyridoxal kinase CRISPR Activation Plasmid (h2) - sc-406685-ACT-2 from Santa Cruz Biotechnology
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pyridoxal kinase Lentiviral Activation Particles (h) - sc-406685-LAC from Santa Cruz Biotechnology
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pyridoxal kinase Lentiviral Activation Particles (h2) - sc-406685-LAC-2 from Santa Cruz Biotechnology
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Pyridoxal Kinase siRNA (h) - sc-61423 from Santa Cruz Biotechnology
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Pyridoxal Kinase shRNA Plasmid (h) - sc-61423-SH from Santa Cruz Biotechnology
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Pyridoxal Kinase shRNA (h) Lentiviral Particles - sc-61423-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU099111 from Sigma-Aldrich
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MISSION® esiRNA - EHU115821 from Sigma-Aldrich
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MISSION® esiRNA - EHU128061 from Sigma-Aldrich
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MISSION® siRNA - SIHK1568 from Sigma-Aldrich
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MISSION® siRNA - SIHK1570 from Sigma-Aldrich
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MISSION® siRNA - SIHK1569 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16587 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16587 from Sigma-Aldrich
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PDXK siRNA (Human) - CRH5634 from Cohesion Biosciences
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Pyridoxal Kinase/PDXK RNAi - H00008566-R02 from Novus Biologicals
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shRNA set against Human PDXK (NM_003681.4) - SHH373140 from Creative biogene
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shRNA set against Human PDXK(NM_003681.4) - SHR103416 from Creative biogene
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Human PDXK siRNA - orb266136 from Biorbyt
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PDXK shRNA Plasmid (Human) - CHH5634 from Cohesion Biosciences
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