Gene Symbol | PI15 |
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Entrez Gene | 51050 |
Alt Symbol | CRISP8, P24TI, P25TI |
Species | Human |
Gene Type | protein-coding |
Description | peptidase inhibitor 15 |
Other Description | 25 kDa trypsin inhibitor|CRISP-8|PI-15|cysteine-rich secretory protein 8|protease inhibitor 15|sugarCrisp |
Swissprots | O43692 Q68CY1 |
Accessions | EAW87037 O43692 AK130318 AK130386 BC074931 AAH74931 BC074932 AAH74932 BC126290 AAI26291 BC126292 AAI26293 CR749657 CAH18451 D45027 BAA25066 HQ258601 ADR83354 XM_005251255 XP_005251312 XM_006716453 XP_006716516 NM_015886 NP_056970 |
Function | Serine protease inhibitor which displays weak inhibitory activity against trypsin. {ECO:0000269|PubMed:8882727}. |
Subcellular Location | Secreted. |
Tissue Specificity | Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland. {ECO:0000269|PubMed:11287197, ECO:0000269|PubMed:9473672}. |
CRISP-8 CRISPR/Cas9 KO Plasmid (h) - sc-412099 from Santa Cruz Biotechnology
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CRISP-8 HDR Plasmid (h) - sc-412099-HDR from Santa Cruz Biotechnology
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CRISP-8 Double Nickase Plasmid (h) - sc-412099-NIC from Santa Cruz Biotechnology
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CRISP-8 Double Nickase Plasmid (h2) - sc-412099-NIC-2 from Santa Cruz Biotechnology
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CRISP-8 CRISPR Activation Plasmid (h) - sc-412099-ACT from Santa Cruz Biotechnology
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CRISP-8 CRISPR Activation Plasmid (h2) - sc-412099-ACT-2 from Santa Cruz Biotechnology
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CRISP-8 Lentiviral Activation Particles (h) - sc-412099-LAC from Santa Cruz Biotechnology
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CRISP-8 Lentiviral Activation Particles (h2) - sc-412099-LAC-2 from Santa Cruz Biotechnology
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CRISP-8 siRNA (h) - sc-77482 from Santa Cruz Biotechnology
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CRISP-8 shRNA Plasmid (h) - sc-77482-SH from Santa Cruz Biotechnology
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CRISP-8 shRNA (h) Lentiviral Particles - sc-77482-V from Santa Cruz Biotechnology
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Protease Inhibitor 15 RNAi - H00051050-R01 from Novus Biologicals
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MISSION® esiRNA - EHU055021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16764 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16764 from Sigma-Aldrich
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PI15 siRNA (Human) - CRH9477 from Cohesion Biosciences
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shRNA set against Human PI15 (NM_015886.3) - SHH375160 from Creative biogene
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PI15 shRNA Plasmid (Human) - CHH9477 from Cohesion Biosciences
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PI15 miRNA 3'UTR clone - MiUTR1H-07878 from Creative biogene
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