Gene Symbol | DNAH7 |
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Entrez Gene | 56171 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | dynein, axonemal, heavy chain 7 |
Other Description | axonemal beta dynein heavy chain 7|axonemal dynein heavy chain 7|ciliary dynein heavy chain 7|dynein heavy chain 7, axonemal|dynein heavy chain-like protein 2|dynein, axonemal, heavy polypeptide 7|hDHC2 |
Swissprots | B8ZZX8 Q8N1Z2 Q53QX7 Q8WXX0 Q9Y2F3 Q4G152 O95492 Q9UMS3 Q68CY5 O00433 Q53S64 Q53T02 |
Accessions | AAY14776 AAY14981 AAY14995 AAY24051 CAB46444 EAW70120 EAW70121 Q8WXX0 AB023161 BAA76788 AF327442 AAL37427 AJ132084 CAA10557 AK094515 BAC04372 BC029567 AAH29567 BP199399 BX117789 CR749651 CAH18445 Z83801 CAB06055 XM_011511487 XP_011509789 XM_011511488 XP_011509790 XM_011511489 XP_011509791 XM_011511490 XP_011509792 XM_011511491 XP_011509793 XM_011511492 XP_011509794 XM_011511493 XP_011509795 XM_011511494 XP_011509796 XM_011511495 XP_011509797 XM_011511496 XP_011509798 XM_011511497 XP_011509799 XR_922968 NM_018897 NP_061720 |
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:11877439}. |
Tissue Specificity | Detected in brain, testis and trachea. Detected in bronchial cells (at protein level). {ECO:0000269|PubMed:11175280, ECO:0000269|PubMed:11877439}. |
Top Pathways | Huntington's disease |
DNAH7 CRISPR/Cas9 KO Plasmid (h) - sc-407082 from Santa Cruz Biotechnology
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DNAH7 HDR Plasmid (h) - sc-407082-HDR from Santa Cruz Biotechnology
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DNAH7 Double Nickase Plasmid (h) - sc-407082-NIC from Santa Cruz Biotechnology
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DNAH7 Double Nickase Plasmid (h2) - sc-407082-NIC-2 from Santa Cruz Biotechnology
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DNAH7 CRISPR Activation Plasmid (h) - sc-407082-ACT from Santa Cruz Biotechnology
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DNAH7 CRISPR Activation Plasmid (h2) - sc-407082-ACT-2 from Santa Cruz Biotechnology
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DNAH7 Lentiviral Activation Particles (h) - sc-407082-LAC from Santa Cruz Biotechnology
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DNAH7 Lentiviral Activation Particles (h2) - sc-407082-LAC-2 from Santa Cruz Biotechnology
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DNAH7 siRNA (h) - sc-94382 from Santa Cruz Biotechnology
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DNAH7 shRNA Plasmid (h) - sc-94382-SH from Santa Cruz Biotechnology
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DNAH7 shRNA (h) Lentiviral Particles - sc-94382-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU071371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7335 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7335 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01510 from Sigma-Aldrich
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DNAH7 siRNA (Human) - CRJ1103 from Cohesion Biosciences
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DNAH7 - MBS8205403 from MyBioSource
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shRNA set against Human DNAH7 (NM_018897.2) - SHH279129 from Creative biogene
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DNAH7 shRNA Plasmid (Human) - CHJ1103 from Cohesion Biosciences
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DNAH7 miRNA 3'UTR clone - MiUTR1H-02900 from Creative biogene
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