| Gene Symbol | AQP9 |
|---|---|
| Entrez Gene | 366 |
| Alt Symbol | AQP-9, HsT17287, SSC1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | aquaporin 9 |
| Other Description | aquaglyceroporin-9|aquaporin-9|small solute channel 1 |
| Swissprots | O43315 Q9NP32 |
| Accessions | AAF27983 CBJ05770 CBJ21222 EAW77532 EAW77533 EAW77534 O43315 AB008775 BAA24864 AF016495 AAF16677 AK300055 BAG61864 AK313214 BAG36029 BC026258 AAH26258 BE042553 CB528930 CR542027 CAG46824 DC410284 NM_020980 NP_066190 |
| Function | Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. {ECO:0000269|PubMed:10564231}. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. |
| Top Pathways | Bile secretion |