Gene Symbol | AQP9 |
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Entrez Gene | 366 |
Alt Symbol | AQP-9, HsT17287, SSC1 |
Species | Human |
Gene Type | protein-coding |
Description | aquaporin 9 |
Other Description | aquaglyceroporin-9|aquaporin-9|small solute channel 1 |
Swissprots | O43315 Q9NP32 |
Accessions | AAF27983 CBJ05770 CBJ21222 EAW77532 EAW77533 EAW77534 O43315 AB008775 BAA24864 AF016495 AAF16677 AK300055 BAG61864 AK313214 BAG36029 BC026258 AAH26258 BE042553 CB528930 CR542027 CAG46824 DC410284 NM_020980 NP_066190 |
Function | Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. {ECO:0000269|PubMed:10564231}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. |
Top Pathways | Bile secretion |
AQP9 CRISPR/Cas9 KO Plasmid (h) - sc-401298 from Santa Cruz Biotechnology
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AQP9 HDR Plasmid (h) - sc-401298-HDR from Santa Cruz Biotechnology
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AQP9 Double Nickase Plasmid (h) - sc-401298-NIC from Santa Cruz Biotechnology
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AQP9 Double Nickase Plasmid (h2) - sc-401298-NIC-2 from Santa Cruz Biotechnology
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AQP9 CRISPR Activation Plasmid (h) - sc-401298-ACT from Santa Cruz Biotechnology
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AQP9 CRISPR Activation Plasmid (h2) - sc-401298-ACT-2 from Santa Cruz Biotechnology
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AQP9 Lentiviral Activation Particles (h) - sc-401298-LAC from Santa Cruz Biotechnology
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AQP9 Lentiviral Activation Particles (h2) - sc-401298-LAC-2 from Santa Cruz Biotechnology
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AQP9 siRNA (h) - sc-42371 from Santa Cruz Biotechnology
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AQP9 shRNA Plasmid (h) - sc-42371-SH from Santa Cruz Biotechnology
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AQP9 shRNA (h) Lentiviral Particles - sc-42371-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU003161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3378 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3378 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13181 from Sigma-Aldrich
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AQP9 siRNA (Human) - CRH0261 from Cohesion Biosciences
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AQP9 - MBS8239270 from MyBioSource
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shRNA set against Human AQP9 (NM_020980.3) - SHH238938 from Creative biogene
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shRNA set against Human AQP9(NM_020980.3) - SHG067465 from Creative biogene
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AQP9 shRNA Plasmid (Human) - CHH0261 from Cohesion Biosciences
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AQP9 miRNA 3'UTR clone - MiUTR1H-00504 from Creative biogene
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