Gene Symbol | MSN |
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Entrez Gene | 4478 |
Alt Symbol | HEL70 |
Species | Human |
Gene Type | protein-coding |
Description | moesin |
Other Description | epididymis luminal protein 70|membrane-organizing extension spike protein |
Swissprots | P26038 |
Accessions | CAB46379 EAX05398 EAX05399 P26038 AK297165 BAH12513 AK308486 AK309354 AK309986 BC001112 AAH01112 BC011827 AAH11827 BC017293 AAH17293 CN386296 DQ892653 ABM83579 DQ895892 ABM86818 EU794636 ACJ13690 M69066 AAA36322 XM_005262269 XP_005262326 XM_011530959 XP_011529261 XM_011530960 XP_011529262 NM_002444 NP_002435 |
Function | Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. {ECO:0000269|PubMed:21549406}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Apical cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956}. |
Tissue Specificity | In all tissues and cultured cells studied. |
Top Pathways | Leukocyte transendothelial migration, Measles, Proteoglycans in cancer, Regulation of actin cytoskeleton |
Moesin Antibody - 3146 from Cell Signaling Technology
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Moesin (Q480) Antibody - 3150 from Cell Signaling Technology
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Ezrin (F-1) - sc-377205 from Santa Cruz Biotechnology
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Ezrin (E-8) - sc-398807 from Santa Cruz Biotechnology
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Ezrin (H-4) - sc-398542 from Santa Cruz Biotechnology
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Moesin (E-10) - sc-13122 from Santa Cruz Biotechnology
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Moesin (C-15) - sc-6410 from Santa Cruz Biotechnology
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Moesin (38/87) - sc-58806 from Santa Cruz Biotechnology
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Moesin (SPM295) - sc-56440 from Santa Cruz Biotechnology
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Moesin (38) - sc-136268 from Santa Cruz Biotechnology
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p-Moesin (Thr 558) - sc-12895 from Santa Cruz Biotechnology
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Anti-Ezrin / Radixin / Moesin antibody - ab118572 from Abcam
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Anti-Moesin (phospho T558) antibody - ab61109 from Abcam
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Anti-Moesin (phospho T558) antibody [EPR2371(2)] - ab177943 from Abcam
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Anti-Moesin antibody - ab196632 from Abcam
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Anti-Moesin antibody - ab61202 from Abcam
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Anti-Moesin antibody [2C12] - ab126825 from Abcam
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Anti-Moesin antibody [EP1863Y] - ab52490 from Abcam
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Anti-Moesin antibody [EPR2428(2)] - ab151542 from Abcam
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Anti-MSN / Moesin Antibody - LS-C178790 from LifeSpan Bioscience
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Anti-MSN / Moesin Antibody (aa458-487, AP) - LS-C263603 from LifeSpan Bioscience
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Anti-MSN / Moesin Antibody (aa531-542) - LS-C34680 from LifeSpan Bioscience
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Anti-MSN / Moesin Antibody (C-Terminus, clone EP1863Y) - LS-C49989 from LifeSpan Bioscience
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Anti-MSN / Moesin Antibody (aa458-487, APC) - LS-C263604 from LifeSpan Bioscience
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Anti-MSN / Moesin Antibody (clone 38/87) IHC-plus⢠- LS-B8628 from LifeSpan Bioscience
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