Gene Symbol | EI24 |
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Entrez Gene | 9538 |
Alt Symbol | EPG4, PIG8, TP53I8 |
Species | Human |
Gene Type | protein-coding |
Description | etoposide induced 2.4 |
Other Description | ectopic P-granules autophagy protein 4 homolog|etoposide-induced protein 2.4 homolog|p53-induced gene 8 protein|tumor protein p53 inducible protein 8 |
Swissprots | B4DKL6 A8K7D6 Q9BUQ1 O14681 |
Accessions | EAW67641 EAW67642 O14681 AB209820 BAD93057 AF010313 AAC39531 AF131850 AK223029 AK291951 BAF84640 AK296620 BAG59228 AK301556 BAG63052 AK315841 BAF98732 AK316539 BAH14910 BC002390 AAH02390 BC029333 BG566671 BM450796 BM467354 BQ936285 DA680745 DB520736 DB567734 DQ891361 ABM82287 DQ894541 ABM85467 XM_011543069 XP_011541371 XM_011543070 XP_011541372 NM_001290135 NP_001277064 NM_004879 NP_004870 NR_110769 NR_110770 NM_001007277 |
Function | Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus membrane {ECO:0000269|PubMed:21154811}; Multi-pass membrane protein {ECO:0000269|PubMed:21154811}. Cytoplasm {ECO:0000269|PubMed:21154811}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | p53 signaling pathway |
EI24 CRISPR/Cas9 KO Plasmid (h) - sc-407053 from Santa Cruz Biotechnology
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EI24 HDR Plasmid (h) - sc-407053-HDR from Santa Cruz Biotechnology
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EI24 Double Nickase Plasmid (h) - sc-407053-NIC from Santa Cruz Biotechnology
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EI24 Double Nickase Plasmid (h2) - sc-407053-NIC-2 from Santa Cruz Biotechnology
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EI24 CRISPR Activation Plasmid (h) - sc-407053-ACT from Santa Cruz Biotechnology
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EI24 CRISPR Activation Plasmid (h2) - sc-407053-ACT-2 from Santa Cruz Biotechnology
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EI24 Lentiviral Activation Particles (h) - sc-407053-LAC from Santa Cruz Biotechnology
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EI24 Lentiviral Activation Particles (h2) - sc-407053-LAC-2 from Santa Cruz Biotechnology
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EI24 siRNA (h) - sc-43748 from Santa Cruz Biotechnology
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EI24 shRNA Plasmid (h) - sc-43748-SH from Santa Cruz Biotechnology
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EI24 shRNA (h) Lentiviral Particles - sc-43748-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU110721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7730 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7730 from Sigma-Aldrich
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EI24 siRNA (Human) - CRH6343 from Cohesion Biosciences
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EI24 - MBS8232010 from MyBioSource
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shRNA set against Human EI24 (NM_004879.3) - SHH284069 from Creative biogene
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shRNA set against Human EI24(NM_001007277.1) - SHH027965 from Creative biogene
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shRNA set against Human EI24(NM_004879.3) - SHH028019 from Creative biogene
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EI24 shRNA Plasmid (Human) - CHH6343 from Cohesion Biosciences
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EI24 miRNA 3'UTR clone - MiUTR1H-03146 from Creative biogene
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EI24 miRNA 3'UTR clone - MiUTR1H-03147 from Creative biogene
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