RBBP7

Gene Symbol RBBP7
Entrez Gene 5931
Alt Symbol RbAp46
Species Human
Gene Type protein-coding
Description retinoblastoma binding protein 7
Other Description G1/S transition control protein-binding protein RbAp46|RBBP-7|histone acetyltransferase type B subunit 2|histone-binding protein RBBP7|nucleosome-remodeling factor subunit RBAP46|retinoblastoma-binding protein 7|retinoblastoma-binding protein RbAp46|retinoblastoma-binding protein p46
Swissprots Q5JP00 Q16576
Accessions EAW98919 EAW98920 EAW98921 Q16576 AK091911 BAG52439 AK127332 AK291567 BAF84256 AK310309 BC114500 AAI14501 BC114501 AAI14502 BQ775345 CN414343 CR541701 CAG46502 DA924163 DB460068 U35143 AAC50231 X72841 CAA51360 XM_011545553 XP_011543855 XM_011545554 XP_011543856 NM_001198719 NP_001185648 NM_002893 NP_002884
Function Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. {ECO:0000269|PubMed:10866654}.
Subcellular Location Nucleus.

RBAP46 Antibody - 4522 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RBAP46 Antibody.

RBAP46 (V415) Antibody - 6882 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RBAP46 (V415) Antibody.

RbAp46 (E-9) - sc-377197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RbAp46 (E-9): sc-377197. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear local-ization.

RbAp46 (N-19) - sc-8272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RbAp46 (N-19): sc-8272. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing nuclear staining.

RbAp46 (L-13) - sc-32654 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RbAp46 (L-13): sc-32654. Western blot analysis of RbAp46 expression in K-562 (A) and NIH/3T3 (B) nuclear extracts.

Anti-RbAp46 antibody - ab3535 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab3535 staining RbAp46 in Hela cells by Immunocytochemistry/ immunofluorescence. 

Anti-RbAp46 antibody - ab84500 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of RbAp46 by Immunohistochemistry on formalin fixed, paraffin embedded section of human ovarian tumor using a 1/250 dilution of ab84500. Detection: DAB staining

Anti-RbAp46 antibody [3A12] - ab119080 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A12
All lanes : Anti-RbAp46 antibody [3A12] (ab119080) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY RbAp46Lysates/proteins at 5 µg per lane.

Anti-RbAp46 antibody [EPR5082] - ab109285 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5082
All lanes : Anti-RbAp46 antibody [EPR5082] (ab109285) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : LnCaP cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-RbAp46 antibody [EPR5083] - ab133245 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5083
All lanes : Anti-RbAp46 antibody [EPR5083] (ab133245) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysate Lane 3 : Y79 cell lysate Lane 4 : HepG2 cell lysate Lysates/proteins at 10 µg per lane.

Anti-RBBP7 / RbAp46 Antibody (aa1-13) - LS-C90942 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody - LS-C9942 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody - LS-C90946 from LifeSpan Bioscience

Prices $475.00
Sizes 150 µg
Host Mouse
Clonality Monoclonal

Anti-RBBP7 / RbAp46 Antibody (N-Terminus) - LS-C131887 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (clone 5A4) - LS-C173368 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A4
IHC of paraffin-embedded Human pancreas tissue using anti-RBBP7 mouse monoclonal antibody.

Anti-RBBP7 / RbAp46 Antibody (aa35-84) - LS-C107661 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBBP7 / RbAp46 antibody LS-C107661 Western blot of Fetal Thymus lysate.

Anti-RBBP7 / RbAp46 Antibody (aa323-372) - LS-C107530 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RBBP7 / RbAp46 antibody LS-C107530 Western blot of HepG2 cell lysate.

Anti-RBBP7 / RbAp46 Antibody (C-Terminus) - LS-C191265 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, AP) - LS-C267898 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, APC) - LS-C267899 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, Biotin) - LS-C267900 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, FITC) - LS-C267901 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, Azide-free, HRP) - LS-C267902 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (aa190-219, PE) - LS-C267903 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBBP7 / RbAp46 Antibody (N-Terminus, AP) - LS-C282161 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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