| Gene Symbol |
CTNNBIP1
|
| Entrez Gene |
56998
|
| Alt Symbol |
ICAT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
catenin, beta interacting protein 1
|
| Other Description |
beta-catenin-interacting protein 1|beta-catenin-interacting protein ICAT|inhibitor of beta-catenin and Tcf-4
|
| Swissprots |
Q9NSA3 Q5T4V2
|
| Accessions |
EAW71631 EAW71632 Q9NSA3 AB021262 BAB03458 BC014300 AAH14300 BC035794 BC146892 AAI46893 BC146896 AAI46897 BC172294 AAI72294 BI226022 CB995652 EU446876 ABZ92405 NM_001012329 NP_001012329 NM_020248 NP_064633
|
| Function |
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. {ECO:0000269|PubMed:12408824}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
| Top Pathways |
Wnt signaling pathway
|
![Western Blot: CTNNBIP1 Overexpression Lysate (Adult Normal) [NBP2-08792] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CTNNBIP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/15701_CTNNBIP1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08792-img0001.jpg)
![Western Blot: CTNNBIP1 Overexpression Lysate (Adult Normal) [NBP2-06663] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CTNNBIP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5412_CTNNBIP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06663-img0001.jpg)