HSPA1L

Gene Symbol HSPA1L
Entrez Gene 3305
Alt Symbol HSP70-1L, HSP70-HOM, HSP70T, hum70t
Species Human
Gene Type protein-coding
Description heat shock 70kDa protein 1-like
Other Description heat shock 10kDa protein 1-like|heat shock 70 kDa protein 1-Hom|heat shock 70 kDa protein 1-like|heat shock 70 kDa protein 1L|heat shock 70kD protein-like 1
Swissprots B0UXW8 A6NNB0 P34931 O75634 Q9UQM1 Q96QC9 Q8NE72 Q2HXR3
Accessions AAA52696 AAA63228 AAD21817 ABC88476 BAB63301 EAX03527 P34931 AK223386 BAD97106 AK295416 BAG58366 AK302179 BAG63545 AK315227 BAG37656 AM392545 CAL37423 AM392811 CAL37689 AM393413 CAL38291 BC034483 AAH34483 BG717447 BX115051 CA443193 D85730 BAA32521 XM_005249070 XP_005249127 XM_005249071 XP_005249128 XM_005249073 XP_005249130 XM_005272816 XP_005272873 XM_005272817 XP_005272874 XM_005274859 XP_005274916 XM_005274861 XP_005274918 XM_005274862 XP_005274919 XM_005274970 XP_005275027 XM_005274973 XP_005275030 XM_005274974 XP_005275031 XM_005275401 XP_005275458 XM_005275402 XP_005275459 XM_011514566 XP_011512868 XM_011546311 XP_011544613 XM_011547246 XP_011545548 XM_011547247 XP_011545549 XM_011547652 XP_011545954 XM_011548238 XP_011546540 XM_011548239 XP_011546541 NM_005527 NP_005518
Function In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity). Positive regulator of PARK2 translocation to damaged mitochondria. {ECO:0000250, ECO:0000269|PubMed:24270810}.
Tissue Specificity Expressed in spermatids. {ECO:0000269|PubMed:9685725}.
Top Pathways Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A, Measles

HSPA1L (B-24) - sc-133679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
HSPA1L (B-24): sc-133679. Western blot analysis of HSPA1L expression in Jurkat whole cell lysate.

HSPA1L (C-6) - sc-393297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSPA1L (C-6): sc-393297. Western blot analysis of HSPA1L expression in mouse testis tissue extract (A) and Hs 181 Tes whole cell lysate (B).

Anti-HSPA1L antibody - ab77155 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-HSPA1L antibody (ab77155) at 1 µg/ml + HeLa cell lysate at 25 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-HSPA1L antibody - ab55289 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
HSPA1L antibody (ab55289) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human testis.

Anti-HSPA1L antibody - ab75115 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HSPA1L antibody (ab75115) at 1/500 dilutionLane 1 : Extracts from HUVEC cellsLane 2 : Extracts from MCF-7 cellsLane 3 : Extracts from MCF-7 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-HSPA1L antibody [HSPA1LB4D2] - ab51486 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HSPA1LB4D2
Lane 1 : Molecular weight markersLane 2 : Anti-HSPA1L antibody [HSPA1LB4D2] (ab51486)Lane 1 : As aboveLane 2 : immunizing recombinant protein

Anti-HSPA1L Antibody - LS-C67262 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-HSPA1L Antibody (aa561-642, clone 10D58, Azide-free) - LS-C183677 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10D58

Anti-HSPA1L Antibody (aa576-603, Biotin) - LS-C236421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa576-603, FITC) - LS-C236422 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa576-603, PE) - LS-C236423 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (C-Terminus) - LS-C81770 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-HSPA1L Antibody (aa576-603, AP) - LS-C246761 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody - LS-C192798 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using HSPA1L antibody.

Anti-HSPA1L Antibody (aa576-603, APC) - LS-C246762 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa576-603, Azide-free, HRP) - LS-C249232 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (clone HSPA1LB4D2) - LS-C184302 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone HSPA1LB4D2
Western blot of immunized recombinant protein using HSPA1L antibody.

Anti-HSPA1L Antibody (aa576-603) - LS-C157819 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HSPA1L Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The HSPA1L antibody detected the HSPA1L protein (arrow).

Anti-HSPA1L Antibody (aa1-641, Biotin) - LS-C298974 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa1-641, Biotin) - LS-C297067 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa1-641, Biotin) - LS-C298977 from LifeSpan Bioscience

Prices $415.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-HSPA1L Antibody (aa1-641, Biotin) - LS-C299237 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa1-641, FITC) - LS-C302713 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPA1L Antibody (aa1-641, FITC) - LS-C302714 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-HSPA1L Antibody (aa1-641, FITC) - LS-C302806 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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