Gene Symbol | PPFIA3 |
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Entrez Gene | 8541 |
Alt Symbol | LPNA3 |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
Other Description | PTPRF-interacting protein alpha-3|liprin|liprin-alpha 3|liprin-alpha-3|protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3|protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3 |
Swissprots | Q9H8B5 Q9UEW4 Q3MJA0 O75145 A8K142 |
Accessions | EAW52457 O75145 AB014554 BAA31629 AF034800 AAC26101 AI346749 AK001525 AK023850 BAB14702 AK025972 AK289757 BAF82446 AK293798 BAG57209 AK308483 BC021255 AAH21255 BC101518 AAI01519 BC101520 AAI01521 BC143470 BU632015 BX111585 DA236900 XM_006723450 XP_006723513 NM_003660 NP_003651 NR_103842 |
Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. {ECO:0000269|PubMed:9624153}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Colocalizes with PTPRF at the cell surface. {ECO:0000250}. |
Tissue Specificity | Expressed only in brain. {ECO:0000269|PubMed:9624153}. |
Liprin α3 CRISPR/Cas9 KO Plasmid (h) - sc-409582 from Santa Cruz Biotechnology
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Liprin α3 HDR Plasmid (h) - sc-409582-HDR from Santa Cruz Biotechnology
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Liprin α3 Double Nickase Plasmid (h) - sc-409582-NIC from Santa Cruz Biotechnology
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Liprin α3 Double Nickase Plasmid (h2) - sc-409582-NIC-2 from Santa Cruz Biotechnology
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Liprin α3 CRISPR Activation Plasmid (h) - sc-409582-ACT from Santa Cruz Biotechnology
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Liprin α3 CRISPR Activation Plasmid (h2) - sc-409582-ACT-2 from Santa Cruz Biotechnology
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Liprin α3 Lentiviral Activation Particles (h) - sc-409582-LAC from Santa Cruz Biotechnology
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Liprin α3 Lentiviral Activation Particles (h2) - sc-409582-LAC-2 from Santa Cruz Biotechnology
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Liprin α3 siRNA (h) - sc-72334 from Santa Cruz Biotechnology
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Liprin α3 shRNA Plasmid (h) - sc-72334-SH from Santa Cruz Biotechnology
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Liprin α3 shRNA (h) Lentiviral Particles - sc-72334-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU100881 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0471 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0469 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0470 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17214 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17214 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06797 from Sigma-Aldrich
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PPFIA3 siRNA (Human) - CRH5612 from Cohesion Biosciences
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PPFIA3 RNAi - H00008541-R01 from Novus Biologicals
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shRNA set against Human PPFIA3 (NM_003660.2) - SHH380496 from Creative biogene
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Human PPFIA3 siRNA - orb266114 from Biorbyt
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PPFIA3 shRNA Plasmid (Human) - CHH5612 from Cohesion Biosciences
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PPFIA3 miRNA 3'UTR clone - MiUTR1H-08143 from Creative biogene
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