AKR1B1

Gene Symbol	AKR1B1
Entrez Gene	231
Alt Symbol	ADR, ALDR1, ALR2, AR
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member B1 (aldose reductase)
Other Description	Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1 member B1|aldose reductase|low Km aldose reductase
Swissprots	Q6FGA4 P15121 Q9UCI9 Q9BS21 Q6ICP2 Q5U031 B2R8N3
Accessions	AAA35561 AAA51712 AAB61992 AAB88851 CBX51392 EAL24070 EAW83814 EAW83815 P15121 AB209796 BAD93033 AF328729 AAN09721 AK311339 AK313439 BAG36230 AL833410 BC000260 AAH00260 BC005387 AAH05387 BC010391 AAH10391 BT019859 AAV38662 CR450351 CAG29347 CR542203 CAG47000 DQ890758 ABM81684 DQ892546 ABM83472 DQ893921 ABM84847 DQ895757 ABM86683 J04795 AAA51713 J05017 AAA51714 J05474 AAA51715 M34720 AAA35560 X15414 CAA33460 XM_005250234 XP_005250291 NM_001628 NP_001619
Function	Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress. {ECO:0000269|PubMed:8435445}.
Top Pathways	Pentose and glucuronate interconversions, Glycerolipid metabolism, Galactose metabolism, Fructose and mannose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human AKR1B1 full length protein - ab117190 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Human AKR1B1 full length protein - ab81765 from Abcam Category Protein Prices $188.00, $577.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human AKR1B1 peptide - ab92665 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Mouse AKR1B1 full length protein - ab202234 from Abcam Category Protein Source E. coli Species Mouse

AKR1B1 / Aldose Reductase Antibody Blocking Peptide - LS-E7055 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1B1 / Aldose Reductase Antibody Blocking Peptide - LS-E17430 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1B1 / Aldose Reductase Antibody Blocking Peptide - LS-E17429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AKR1B1 Protein - NBC1-22925 from Novus Biologicals Category Protein Prices $249.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human AKR1B1 Protein - H00000231-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AKR1B1 Recombinant Protein - H00000231-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AKR1B1 Recombinant Protein - P3474 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

AKR1B1 Peptide - P1226 from Novus Biologicals Category Peptide Species Human

AKR1B1-Antibody-C-term-Blocking-Peptide - BP2735b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AKR1B1 Protein (OPPA02001) - OPPA02001 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human AKR1B1 His tag protein - orb84767 from Biorbyt Category Protein Prices $323.00, $527.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human Aldose Reductase protein - orb90020 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli

AKR1B1 Blocking Peptide - 33R-1528 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AKR1B1 Blocking Peptide - 33R-7728 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Akr1b1 protein (His tag) - 80R-4116 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Alcohol dehydrogenase protein - 30R-1433 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

Aldose reductase protein - 30R-1234 from Fitzgerald Category Protein Prices $250.00 Sizes 100 µg Source E.coli

Aldose Reductase Blocking Peptide - abx062018 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

AKR1B1 / ALDR1 (1-316) - AR09146PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

AKR1B1 / ALDR1 (1-316) - AR09146PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

AKR1B1 / ALDR1 - H00000231-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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