Gene Symbol | SIAE |
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Entrez Gene | 54414 |
Alt Symbol | AIS6, CSE-C, CSEC, LSE, YSG2 |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid acetylesterase |
Other Description | H-Lse|cytosolic sialic acid 9-O-acetylesterase homolog|sialate O-acetylesterase|sialic acid-specific acetylesterase II |
Swissprots | Q9NT71 Q9HAU7 B3KPB0 Q8IUT9 Q9HAT2 |
Accessions | EAW67591 Q9HAT2 AA938533 AF300796 AAG15386 AF303378 AAG14897 AK056093 BAG51622 AK092224 AL137496 CAB70771 BC022456 BC040966 BC068450 AAH68450 CA778291 DB027544 EU831959 ACE87400 XM_005271592 XP_005271649 XM_011542874 XP_011541176 NM_001199922 NP_001186851 NM_170601 NP_733746 NM_018978 |
Function | Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. |
Subcellular Location | Lysosome {ECO:0000305}. Secreted. |
Tissue Specificity | Widely expressed with high expression in the testis, prostate, and colon. {ECO:0000269|PubMed:15292578}. |
SIAE CRISPR/Cas9 KO Plasmid (h) - sc-412274 from Santa Cruz Biotechnology
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SIAE HDR Plasmid (h) - sc-412274-HDR from Santa Cruz Biotechnology
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SIAE Double Nickase Plasmid (h) - sc-412274-NIC from Santa Cruz Biotechnology
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SIAE Double Nickase Plasmid (h2) - sc-412274-NIC-2 from Santa Cruz Biotechnology
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SIAE CRISPR Activation Plasmid (h) - sc-412274-ACT from Santa Cruz Biotechnology
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SIAE CRISPR Activation Plasmid (h2) - sc-412274-ACT-2 from Santa Cruz Biotechnology
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SIAE Lentiviral Activation Particles (h) - sc-412274-LAC from Santa Cruz Biotechnology
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SIAE Lentiviral Activation Particles (h2) - sc-412274-LAC-2 from Santa Cruz Biotechnology
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SIAE siRNA (h) - sc-96456 from Santa Cruz Biotechnology
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SIAE shRNA Plasmid (h) - sc-96456-SH from Santa Cruz Biotechnology
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SIAE shRNA (h) Lentiviral Particles - sc-96456-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU063811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19319 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19319 from Sigma-Aldrich
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SIAE siRNA (Human) - CRJ0049 from Cohesion Biosciences
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SIAE - MBS8205986 from MyBioSource
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shRNA set against Human SIAE (NM_170601.4) - SHH407320 from Creative biogene
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Human SIAE siRNA - orb270550 from Biorbyt
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SIAE shRNA Plasmid (Human) - CHJ0049 from Cohesion Biosciences
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SIAE miRNA 3'UTR clone - MiUTR3H-11019 from Creative biogene
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