| Gene Symbol |
MMP3
|
| Entrez Gene |
4314
|
| Alt Symbol |
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
matrix metallopeptidase 3
|
| Other Description |
matrix metallopeptidase 3 (stromelysin 1, progelatinase)|matrix metalloproteinase 3 (stromelysin 1, progelatinase)|matrix metalloproteinase-3|proteoglycanase|stromelysin-1|transin-1
|
| Swissprots |
P08254 B2R8B8 Q6GRF8 Q3B7S0
|
| Accessions |
AAB36942 AAD14909 AAK95247 AAN86644 AAO65616 EAW67032 P08254 AI628953 AK223283 BAD97003 AK223291 BAD97011 AK313310 BAG36115 BC069676 AAH69676 BC069716 AAH69716 BC074815 AAH74815 BC074869 AAH74869 BC105954 AAI05955 BC107490 AAI07491 BC107491 AAI07492 DQ399598 ABD92797 HQ447430 ADQ31916 J03209 AAA36321 X05232 CAA28859 NM_002422 NP_002413
|
| Function |
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000305}.
|
| Top Pathways |
Rheumatoid arthritis, TNF signaling pathway, Transcriptional misregulation in cancer
|
![Western Blot: MMP3 Overexpression Lysate (Adult Normal) [NBL1-13159] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MMP3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6800_MMP3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13159-img0002.jpg)