| Gene Symbol |
SOAT1
|
| Entrez Gene |
102121286
|
| Alt Symbol |
-
|
| Species |
Monkey
|
| Gene Type |
protein-coding
|
| Description |
sterol O-acyltransferase 1
|
| Other Description |
-
|
| Swissprots |
O77761
|
| Accessions |
AB168948 BAE01048 NM_001287292 NP_001274221 XM_005540113 XP_005540170
|
| Function |
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in most tissues, but most strongly in the adrenal gland. Expressed more strongly in liver Kupffer cells than in hepatocytes.
|
| Top Pathways |
Steroid biosynthesis
|