| Gene Symbol |
B3GNT8
|
| Entrez Gene |
374907
|
| Alt Symbol |
B3GALT7, BGALT15, beta3Gn-T8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
|
| Other Description |
BGnT-8|UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 7|beta galactosyltransferase BGALT15|beta-1,3-Gn-T8|beta-1,3-N-acetylglucosaminyltransferase 8|beta1,3-N-acetylglucosaminyltransferase 8
|
| Swissprots |
Q7Z7M8
|
| Accessions |
Q7Z7M8 AB175895 BAD86525 AJ419172 CAD11601 AY277592 AAP34405 BC156488 AAI56489 BC172521 AAI72521 XM_011526934 XP_011525236 NM_198540 NP_940942
|
| Function |
Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans. {ECO:0000269|PubMed:15620693, ECO:0000269|PubMed:15917431}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NY97}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NY97}.
|
| Tissue Specificity |
Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines. {ECO:0000269|PubMed:15486459, ECO:0000269|PubMed:15620693}.
|