Gene Symbol |
FAF2
|
Entrez Gene |
23197
|
Alt Symbol |
ETEA, UBXD8, UBXN3B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Fas associated factor family member 2
|
Other Description |
FAS-associated factor 2|UBX domain containing 8|UBX domain protein 3B|UBX domain-containing protein 3B|UBX domain-containing protein 8|expressed in T-cells and eosinophils in atopic dermatitis
|
Swissprots |
O94963 Q96CS3 Q9BRP2 Q9BVM7 Q8IUF2
|
Accessions |
EAW85073 EAW85074 EAW85075 Q96CS3 AB020694 BAA74910 AB088120 BAC22491 AK304346 BAG65190 AL706430 BC001069 AAH01069 BC006145 AAH06145 BC014001 AAH14001 BC015791 BC021065 DQ892700 ABM83626 DQ896293 ABM87292 XM_011534475 XP_011532777 XM_011534476 XP_011532778 NM_014613 NP_055428
|
Function |
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. {ECO:0000269|PubMed:18711132}.
|
Subcellular Location |
Cytoplasm. Lipid droplet. Endoplasmic reticulum.
|
Tissue Specificity |
Broadly expressed, with highest levels in brain. {ECO:0000269|PubMed:12372427}.
|