Gene Symbol | Hadh |
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Entrez Gene | 15107 |
Alt Symbol | AA409008, AU019341, AW742602, HCDH, Hadhsc, Schad |
Species | Mouse |
Gene Type | protein-coding |
Description | hydroxyacyl-Coenzyme A dehydrogenase |
Other Description | L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain|hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase|medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase|short chain 3-hydroxyacyl-CoA dehydrogenase|short-chain 3-hydroxyacyl-CoA dehydrogenase |
Swissprots | Q3TF75 Q3UFI0 Q925U9 Q8K149 Q3THK8 Q61425 |
Accessions | AAK54642 EDL12203 Q61425 AI845880 AK075609 AK132260 BAE21064 AK148481 AK148486 BAE28581 AK167024 BAE39197 AK168238 BAE40188 AK168877 BAE40695 AK169238 AK169261 BAE41023 AK197246 AK206850 AK208263 AK211835 BC028833 AAH28833 BC064712 AAH64712 D29639 BAA06122 NM_008212 NP_032238 |
Function | Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Lysine degradation, Fatty acid elongation, Fatty acid degradation, Tryptophan metabolism, Valine, leucine and isoleucine degradation |
HADHSC CRISPR/Cas9 KO Plasmid (m) - sc-420789 from Santa Cruz Biotechnology
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HADHSC HDR Plasmid (m) - sc-420789-HDR from Santa Cruz Biotechnology
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HADHSC Double Nickase Plasmid (m) - sc-420789-NIC from Santa Cruz Biotechnology
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HADHSC Double Nickase Plasmid (m2) - sc-420789-NIC-2 from Santa Cruz Biotechnology
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HADHSC CRISPR Activation Plasmid (m) - sc-420789-ACT from Santa Cruz Biotechnology
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HADHSC CRISPR Activation Plasmid (m2) - sc-420789-ACT-2 from Santa Cruz Biotechnology
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HADHSC Lentiviral Activation Particles (m) - sc-420789-LAC from Santa Cruz Biotechnology
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HADHSC Lentiviral Activation Particles (m2) - sc-420789-LAC-2 from Santa Cruz Biotechnology
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HADHSC siRNA (m) - sc-75223 from Santa Cruz Biotechnology
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HADHSC shRNA Plasmid (m) - sc-75223-SH from Santa Cruz Biotechnology
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HADHSC shRNA (m) Lentiviral Particles - sc-75223-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU066991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33068 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33068 from Sigma-Aldrich
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HADH siRNA (Mouse) - CRM1769 from Cohesion Biosciences
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HADH - MBS8221664 from MyBioSource
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shRNA set against Mouse HADH (NM_008212.3) - SHH310141 from Creative biogene
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HADHSC CRISPR/Cas9 KO Plasmid (m2) - sc-420789-KO-2 from Santa Cruz Biotechnology
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HADHSC HDR Plasmid (m2) - sc-420789-HDR-2 from Santa Cruz Biotechnology
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HADH shRNA Plasmid (Mouse) - CHM1769 from Cohesion Biosciences
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HADH miRNA 3'UTR clone - MiUTR1M-05530 from Creative biogene
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