| Gene Symbol |
GPR39
|
| Entrez Gene |
2863
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 39
|
| Other Description |
G-protein coupled receptor 39
|
| Swissprots |
Q08AS2 O43194 Q53R01 B2RC12 B6V9G4
|
| Accessions |
AAX93106 AAY24154 CAK96158 CAS92673 EAX11678 EAX11679 EAX11680 O43194 AF034633 AAC26082 AI459805 AK122643 BAG53636 AK123759 BAG53953 AK314895 BAG37409 BC125046 AAI25047 BC125047 AAI25048 BK005609 DAA06055 BM981455 DA596795 DA636860 DA653793 EU076432 ABU53902 FJ348258 ACI96302 XM_011511021 XP_011509323 NM_001508 NP_001499
|
| Function |
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in many tissues, including the stomach, intestine and hypothalamus. {ECO:0000269|PubMed:9441746}.
|