Msh3

Gene Symbol Msh3
Entrez Gene 17686
Alt Symbol D13Em1, Rep-3, Rep3
Species Mouse
Gene Type protein-coding
Description mutS homolog 3 (E. coli)
Other Description DNA mismatch repair protein Msh3|REP-1|protein repair-1|protein repair-3
Swissprots P13705
Accessions AAB60710 AAB60711 P13705 AK011426 AK040616 BAC30646 AK078467 BAE43365 AK083388 AK133907 AK161089 AK161430 BAE36392 BC025063 BC040784 AAH40784 BC150759 AAI50760 BQ571929 BY710130 CK022909 M24919 AAA40051 M80360 AAA40052 XM_006517541 XP_006517604 XM_006517542 XP_006517605 XM_006517543 XP_006517606 XM_006517545 XP_006517608 XM_006517547 XP_006517610 XM_011244626 XP_011242928 NM_010829 NP_034959
Function Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion- deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis (By similarity). {ECO:0000250}.
Top Pathways Mismatch repair, Colorectal cancer

MSH3 CRISPR/Cas9 KO Plasmid (m) - sc-421716 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 HDR Plasmid (m) - sc-421716-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 Double Nickase Plasmid (m) - sc-421716-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 Double Nickase Plasmid (m2) - sc-421716-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 CRISPR Activation Plasmid (m) - sc-421716-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 CRISPR Activation Plasmid (m2) - sc-421716-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 Lentiviral Activation Particles (m) - sc-421716-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 Lentiviral Activation Particles (m2) - sc-421716-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MSH3 siRNA (m) - sc-35972 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MSH3 shRNA Plasmid (m) - sc-35972-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MSH3 shRNA (m) Lentiviral Particles - sc-35972-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU083601 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN35879 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35879 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MSH3 siRNA (Mouse) - CRM2599 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Msh3 (NM_010829.2) - SHH345632 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Msh3(NM_010829.2) - SHH203555 from Creative biogene

Category siRNA
Species Reactivities Mouse

MSH3 shRNA Plasmid (Mouse) - CHM2599 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

MSH3 miRNA 3'UTR clone - MiUTR1M-07333 from Creative biogene

Species Reactivities Mouse
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