| Gene Symbol |
AKAP7
|
| Entrez Gene |
9465
|
| Alt Symbol |
AKAP15, AKAP18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 7
|
| Other Description |
A-kinase anchor protein 18 kDa|A-kinase anchor protein 7 isoform gamma|A-kinase anchor protein 7 isoforms alpha and beta|A-kinase anchor protein 9 kDa|AKAP 18|AKAP-7 isoform gamma|AKAP-7 isoforms alpha and beta|PRKA7 isoform gamma|PRKA7 isoforms alpha/beta
|
| Swissprots |
Q5TBR9 A8K2K6 Q9HCZ8 Q9P0M2 Q9P0G4 Q5TBS0 O43687 B4DUC3
|
| Accessions |
EAW48057 EAW48058 EAW48059 EAW48060 O43687 Q9P0M2 AB451273 BAG70087 AB451400 BAG70214 AF152929 AAF28106 AF161075 AAF26676 AK290271 BAF82960 AK300587 BAG62285 AK311820 BAG34762 AW236482 BC016927 AAH16927 BC063499 AAH63499 BC073847 AAH73847 BC094732 AAH94732 BC110897 AAI10898 BC118601 AAI18602 BC118606 AAI18607 BC128398 AAI28399 BC128399 AAI28400 BC141926 AAI41927 BC141927 AAI41928 BC152940 AAI52941 BC156906 AAI56907 DA144596 DN998807 XM_005267228 XP_005267285 XM_005267229 XP_005267286 XM_006715614 XP_006715677 XM_011536262 XP_011534564 XR_427979 XR_942636 NM_004842 NP_004833 NM_016377 NP_057461 NM_138633 NP_619539
|
| Function |
Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane- associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. {ECO:0000269|PubMed:10613906, ECO:0000269|PubMed:17244820}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:10613906}.
|
| Tissue Specificity |
Expressed in brain, heart, lung, pancreas and placenta. {ECO:0000269|PubMed:10613906}.
|