Gene Symbol |
UGT3A2
|
Entrez Gene |
167127
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
UDP glycosyltransferase 3 family, polypeptide A2
|
Other Description |
UDP-glucuronosyltransferase 3A2|UDPGT 3A2
|
Swissprots |
Q8NBP2 E9PFK7 B4DUQ7 Q3SY77 Q6UXC4
|
Accessions |
CAI72084 EAW55931 Q3SY77 AK075383 BAC11583 AK300751 BAG62419 AK303154 BAG64257 AY358416 AAQ88782 BC103924 AAI03925 BC103925 AAI03926 DB110369 XM_011513988 XP_011512290 NM_001168316 NP_001161788 NM_174914 NP_777574 NR_031764
|
Function |
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|