Gene Symbol |
Cenpl
|
Entrez Gene |
289150
|
Alt Symbol |
RGD1311868
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
centromere protein L
|
Other Description |
CENP-L
|
Swissprots |
Q0P5Q6 Q3ZAU7
|
Accessions |
EDM09423 EDM09424 Q3ZAU7 BC079467 AAH79467 BC089893 BC103642 AAI03643 XM_006250099 XP_006250161 XM_006250100 XP_006250162 NM_001033061 NP_001028233 NM_001244761 NP_001231690
|
Function |
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity). {ECO:0000250}.
|