Gene Symbol | ELAVL3 |
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Entrez Gene | 1995 |
Alt Symbol | HUC, HUCL, PLE21 |
Species | Human |
Gene Type | protein-coding |
Description | ELAV like neuron-specific RNA binding protein 3 |
Other Description | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)|ELAV-like protein 3|Hu antigen C|hu-antigen C|paraneoplastic cerebellar degeneration-associated antigen|paraneoplastic limbic encephalitis antigen 21 |
Swissprots | Q96CL8 Q96QS9 Q16135 Q14576 |
Accessions | CAC21655 CCQ43760 EAW84220 EAW84221 Q14576 AI199100 AY034002 AAK57545 AY036909 AAK67714 BC011875 AAH11875 BC014144 BC080533 BI117592 D26158 BAA21838 L26405 AAA58677 XM_011527778 XP_011526080 XM_011527779 XP_011526081 XR_936166 NM_001420 NP_001411 NM_032281 NP_115657 |
Function | Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance. {ECO:0000250, ECO:0000269|PubMed:10710437}. |
Tissue Specificity | Brain specific. |
HuC CRISPR/Cas9 KO Plasmid (h) - sc-400172 from Santa Cruz Biotechnology
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HuC HDR Plasmid (h) - sc-400172-HDR from Santa Cruz Biotechnology
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HuC Double Nickase Plasmid (h) - sc-400172-NIC from Santa Cruz Biotechnology
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HuC Double Nickase Plasmid (h2) - sc-400172-NIC-2 from Santa Cruz Biotechnology
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HuC CRISPR Activation Plasmid (h) - sc-400172-ACT from Santa Cruz Biotechnology
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HuC CRISPR Activation Plasmid (h2) - sc-400172-ACT-2 from Santa Cruz Biotechnology
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HuC Lentiviral Activation Particles (h) - sc-400172-LAC from Santa Cruz Biotechnology
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HuC Lentiviral Activation Particles (h2) - sc-400172-LAC-2 from Santa Cruz Biotechnology
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HuC siRNA (h) - sc-37833 from Santa Cruz Biotechnology
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HuC shRNA Plasmid (h) - sc-37833-SH from Santa Cruz Biotechnology
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HuC shRNA (h) Lentiviral Particles - sc-37833-V from Santa Cruz Biotechnology
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HuC RNAi - H00001995-R01 from Novus Biologicals
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HuC RNAi - H00001995-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN7797 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7797 from Sigma-Aldrich
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ELAVL3 siRNA (Human) - CRH1379 from Cohesion Biosciences
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ELAVL3 - MBS8204777 from MyBioSource
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shRNA set against Human ELAVL3 (NM_001420.3) - SHH284973 from Creative biogene
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shRNA set against Human ELAVL3(NM_001420.3) - SHH030899 from Creative biogene
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shRNA set against Human ELAVL3(NM_032281.2) - SHH030953 from Creative biogene
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HuC CRISPR/Cas9 KO Plasmid (h2) - sc-400172-KO-2 from Santa Cruz Biotechnology
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HuC HDR Plasmid (h2) - sc-400172-HDR-2 from Santa Cruz Biotechnology
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Human ELAVL3 siRNA - orb261881 from Biorbyt
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ELAVL3 shRNA Plasmid (Human) - CHH1379 from Cohesion Biosciences
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ELAVL3 miRNA 3'UTR clone - MiUTR1H-03187 from Creative biogene
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