Gene Symbol |
BRI3BP
|
Entrez Gene |
140707
|
Alt Symbol |
BNAS1, HCCR-1, HCCR-2, HCCRBP-1, KG19
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
BRI3 binding protein
|
Other Description |
BRI3-binding protein|I3-binding protein|cervical cancer 1 proto-oncogene-binding protein KG19|cervical cancer oncogene binding protein
|
Swissprots |
Q8WY23 Q8WY22
|
Accessions |
EAW98470 EAW98471 Q8WY22 AF283671 AAL33003 AF284094 AAL54382 AF441865 AAN76689 AK055703 BC034525 AAH34525 CA488612 XM_011537940 XP_011536242 NM_080626 NP_542193
|
Function |
Involved in tumorigenesis and may function by stabilizing p53/TP53. {ECO:0000269|PubMed:17943721}.
|
Subcellular Location |
Mitochondrion outer membrane {ECO:0000305|PubMed:17943721}; Multi-pass membrane protein {ECO:0000305|PubMed:17943721}.
|
Tissue Specificity |
Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas. {ECO:0000269|PubMed:11860200, ECO:0000269|PubMed:17943721}.
|