| Gene Symbol |
IL20RB
|
| Entrez Gene |
53833
|
| Alt Symbol |
DIRS1, FNDC6, IL-20R2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 20 receptor beta
|
| Other Description |
IL-20 receptor subunit beta|IL-20R-beta|IL-20RB|fibronectin type III domain containing 6|interleukin-20 receptor II|interleukin-20 receptor subunit beta
|
| Swissprots |
B4DL40 Q8TAJ7 Q8IYY5 Q6P438 Q6UXL0
|
| Accessions |
CAJ09895 CAJ09909 CAJ65781 CAM31821 CBJ18627 CBX89254 EAW79099 EAW79100 EAW79101 EAW79102 EAW79103 EAW79104 Q6UXL0 AK296832 BAG59402 AK316084 BAH14455 AY358305 AAQ88672 BC027449 BC033292 AAH33292 BC063696 AAH63696 HQ447455 ADQ31941 JF432484 ADZ15701 XM_006713665 XP_006713728 XM_011512910 XP_011511212 XM_011512911 XP_011511213 NM_144717 NP_653318
|
| Function |
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
|