Gene Symbol | CHAD |
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Entrez Gene | 1101 |
Alt Symbol | SLRR4A |
Species | Human |
Gene Type | protein-coding |
Description | chondroadherin |
Other Description | cartilage leucine-rich protein|chondroadherin proteoglycan |
Swissprots | O15335 A8K812 Q96RJ5 Q6GTU0 |
Accessions | AAC13410 EAW94613 EAW94614 O15335 AF371328 AAK51556 AK292177 BAF84866 BC036360 AAH36360 BC073974 AAH73974 BQ181527 JF432155 ADZ15372 XM_011524214 XP_011522516 NM_001267 NP_001258 |
Function | Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Present in chondrocytes at all ages. |
Top Pathways | Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway |
CHAD CRISPR/Cas9 KO Plasmid (h) - sc-408714 from Santa Cruz Biotechnology
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CHAD HDR Plasmid (h) - sc-408714-HDR from Santa Cruz Biotechnology
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CHAD Double Nickase Plasmid (h) - sc-408714-NIC from Santa Cruz Biotechnology
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CHAD Double Nickase Plasmid (h2) - sc-408714-NIC-2 from Santa Cruz Biotechnology
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CHAD CRISPR Activation Plasmid (h) - sc-408714-ACT from Santa Cruz Biotechnology
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CHAD CRISPR Activation Plasmid (h2) - sc-408714-ACT-2 from Santa Cruz Biotechnology
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CHAD Lentiviral Activation Particles (h) - sc-408714-LAC from Santa Cruz Biotechnology
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CHAD Lentiviral Activation Particles (h2) - sc-408714-LAC-2 from Santa Cruz Biotechnology
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CHAD siRNA (h) - sc-93796 from Santa Cruz Biotechnology
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CHAD shRNA Plasmid (h) - sc-93796-SH from Santa Cruz Biotechnology
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CHAD shRNA (h) Lentiviral Particles - sc-93796-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6027 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6027 from Sigma-Aldrich
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CHAD siRNA (Human) - CRH0783 from Cohesion Biosciences
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Chondroadherin RNAi - H00001101-R01 from Novus Biologicals
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CHAD - MBS8235556 from MyBioSource
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Human CHAD siRNA - orb261285 from Biorbyt
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CHAD shRNA Plasmid (Human) - CHH0783 from Cohesion Biosciences
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