| Gene Symbol |
KLHL31
|
| Entrez Gene |
401265
|
| Alt Symbol |
BKLHD6, KBTBD1, KLHL, bA345L23.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kelch-like family member 31
|
| Other Description |
BTB and kelch domain-containing protein 6|kelch repeat and BTB (POZ) domain containing 1|kelch repeat and BTB domain-containing protein 1|kelch-like protein 31|kelch-like protein KLHL
|
| Swissprots |
B2RP49 A6N9J2 Q9H511
|
| Accessions |
EAX04428 Q9H511 BC137267 AAI37268 BC137269 AAI37270 EF633513 ABR23528 XM_005249107 XP_005249164 NM_001003760 NP_001003760
|
| Function |
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). {ECO:0000269|PubMed:18719355}.
|
| Tissue Specificity |
Strongly expressed in skeletal muscle and weakly in heart. According to PubMed:15302408, not expressed in other tissues. According to PubMed:18719355, abundantly expressed in both embryonic skeletal and heart tissues. {ECO:0000269|PubMed:15302408, ECO:0000269|PubMed:18719355}.
|