Gene Symbol | PANK2 |
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Entrez Gene | 80025 |
Alt Symbol | C20orf48, HARP, HSS, NBIA1, PKAN |
Species | Human |
Gene Type | protein-coding |
Description | pantothenate kinase 2 |
Other Description | Hallervorden-Spatz syndrome|pantothenate kinase 2, mitochondrial|pantothenic acid kinase 2 |
Swissprots | B1AK33 Q8TCR5 Q9BZ23 Q8N7Q4 Q7RTX5 Q5T7I4 D3DVZ0 B2Z3X0 Q9HAF2 Q5T7I2 Q9BYW5 |
Accessions | ACD11492 EAX10476 EAX10478 Q9BZ23 AF086501 AF494409 AAN32907 AK021791 BAB13897 AK097796 BAC05173 AK310190 AL519408 AL532307 AL713654 CAD28463 BC009421 BC065019 AAH65019 BC093633 AAH93633 BC101569 AAI01570 BC101571 AAI01572 BC107724 BC142976 BF698882 BK000010 DAA00004 XM_005260835 XP_005260892 XM_005260836 XP_005260893 XM_006723631 XP_006723694 XM_011529364 XP_011527666 XM_011529365 XP_011527667 NM_024960 NP_079236 NM_153638 NP_705902 NM_153640 NP_705904 NM_153637 NM_153639 NM_153641 |
Function | May be the master regulator of the CoA biosynthesis. {ECO:0000250}. |
Subcellular Location | Isoform 3: Cytoplasm {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11479594}. |
Top Pathways | Pantothenate and CoA biosynthesis |
PANK2 CRISPR/Cas9 KO Plasmid (h) - sc-405120 from Santa Cruz Biotechnology
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PANK2 HDR Plasmid (h) - sc-405120-HDR from Santa Cruz Biotechnology
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PANK2 Double Nickase Plasmid (h) - sc-405120-NIC from Santa Cruz Biotechnology
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PANK2 Double Nickase Plasmid (h2) - sc-405120-NIC-2 from Santa Cruz Biotechnology
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PANK2 CRISPR Activation Plasmid (h) - sc-405120-ACT from Santa Cruz Biotechnology
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PANK2 CRISPR Activation Plasmid (h2) - sc-405120-ACT-2 from Santa Cruz Biotechnology
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PANK2 Lentiviral Activation Particles (h) - sc-405120-LAC from Santa Cruz Biotechnology
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PANK2 Lentiviral Activation Particles (h2) - sc-405120-LAC-2 from Santa Cruz Biotechnology
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PANK2 siRNA (h) - sc-76042 from Santa Cruz Biotechnology
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PANK2 shRNA Plasmid (h) - sc-76042-SH from Santa Cruz Biotechnology
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PANK2 shRNA (h) Lentiviral Particles - sc-76042-V from Santa Cruz Biotechnology
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PANK2 RNAi - H00080025-R09 from Novus Biologicals
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PANK2 RNAi - H00080025-R10 from Novus Biologicals
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PANK2 RNAi - H00080025-R08 from Novus Biologicals
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PANK2 RNAi - H00080025-R07 from Novus Biologicals
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PANK2 RNAi - H00080025-R11 from Novus Biologicals
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MISSION® esiRNA - EHU062111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16304 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16304 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04530 from Sigma-Aldrich
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PANK2 siRNA (Human) - CRJ2734 from Cohesion Biosciences
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PANK2 RNAi - H00080025-R12 from Novus Biologicals
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shRNA set against Human PANK2 (NM_024960.4) - SHH370356 from Creative biogene
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shRNA set against Human PANK2(NM_153638.2) - SHR086836 from Creative biogene
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shRNA set against Human PANK2(NM_024960.4) - SHR086854 from Creative biogene
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