Gene Symbol | NDUFV1 |
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Entrez Gene | 4723 |
Alt Symbol | CI-51K, CI51KD, UQOR1 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
Other Description | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial|NADH-ubiquinone oxidoreductase 51 kDa subunit|complex I 51 kda subunit|complex I 51kDa subunit|complex I, mitochondrial respiratory chain|mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1|mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit |
Swissprots | Q6IBR3 Q16104 Q96HS7 Q96BF8 O60940 O60924 P49821 |
Accessions | AAC39750 ADP90734 ADP90735 ADP90736 ADP90737 ADP90738 ADP90739 ADP90740 ADP90741 ADP90742 ADP90743 ADP90744 ADP90745 ADP90746 ADP90747 ADP90748 ADP90749 ADP90750 ADP90751 ADP90752 ADP90753 ADP90754 ADP90755 ADP90756 ADP90757 ADP90758 ADP90759 ADP90760 ADP90761 ADP90762 ADP90763 ADP90764 ADP90765 ADP90766 ADP90767 ADP90768 ADP90769 ADP90770 ADP90771 ADP90772 ADP90773 CAA76757 CAR98247 EAW74652 EAW74653 EAW74654 EAW74655 EAW74656 P49821 AF053070 AAC39722 AF092131 AAD40373 AK055875 AK223061 BAD96781 AK293522 BAG57004 AK300726 BAG62399 AK310537 AK316122 BAH14493 AU099299 BC007619 AAH07619 BC008146 AAH08146 BC015645 AAH15645 BP254989 CR456739 CAG33020 DB532599 DQ893236 ABM84162 DQ896566 ABM87565 S67973 AAB29698 NM_001166102 NP_001159574 NM_007103 NP_009034 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFV1 CRISPR/Cas9 KO Plasmid (h) - sc-404372 from Santa Cruz Biotechnology
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NDUFV1 HDR Plasmid (h) - sc-404372-HDR from Santa Cruz Biotechnology
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NDUFV1 Double Nickase Plasmid (h) - sc-404372-NIC from Santa Cruz Biotechnology
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NDUFV1 Double Nickase Plasmid (h2) - sc-404372-NIC-2 from Santa Cruz Biotechnology
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NDUFV1 CRISPR Activation Plasmid (h) - sc-404372-ACT from Santa Cruz Biotechnology
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NDUFV1 CRISPR Activation Plasmid (h2) - sc-404372-ACT-2 from Santa Cruz Biotechnology
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NDUFV1 Lentiviral Activation Particles (h) - sc-404372-LAC from Santa Cruz Biotechnology
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NDUFV1 Lentiviral Activation Particles (h2) - sc-404372-LAC-2 from Santa Cruz Biotechnology
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NDUFV1 siRNA (h) - sc-96604 from Santa Cruz Biotechnology
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NDUFV1 shRNA Plasmid (h) - sc-96604-SH from Santa Cruz Biotechnology
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NDUFV1 shRNA (h) Lentiviral Particles - sc-96604-V from Santa Cruz Biotechnology
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NDUFV1 RNAi - H00004723-R01V from Novus Biologicals
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MISSION® esiRNA - EHU033501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15174 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15174 from Sigma-Aldrich
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NDUFV1 siRNA (Human) - CRH3136 from Cohesion Biosciences
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NDUFV1 RNAi - H00004723-R01 from Novus Biologicals
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Human NDUFV1 siRNA - orb263638 from Biorbyt
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NDUFV1 shRNA Plasmid (Human) - CHH3136 from Cohesion Biosciences
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