| Gene Symbol |
SLC25A17
|
| Entrez Gene |
10478
|
| Alt Symbol |
PMP34
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
|
| Other Description |
peroxisomal membrane protein PMP34|solute carrier family 25 member 17
|
| Swissprots |
Q9UGY7 Q5TFL0 A8KA59 Q9UGW8 O43808
|
| Accessions |
CAH56802 EAW60389 EAW60390 EAW60391 EAW60392 EAW60393 O43808 AK094062 AK292924 BAF85613 AK298215 BAG60485 AK300553 BAG62259 AU123445 BC005957 AAH05957 BC012998 AAH12998 BC024741 BC039064 BQ440957 BU595416 BU686766 BX352732 BX647991 CR456577 CAG30463 CU013178 CAK54609 CU013466 CAK54908 DC397321 DQ893138 ABM84064 DQ896422 ABM87421 Y12860 CAA73367 NM_001282726 NP_001269655 NM_001282727 NP_001269656 NM_006358 NP_006349 NR_104235 NR_104236 NR_104237 NR_104238
|
| Function |
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro. {ECO:0000269|PubMed:12445829, ECO:0000269|PubMed:22185573}.
|
| Subcellular Location |
Cytoplasm. Peroxisome membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Ubiquitous. Expressed in liver. {ECO:0000269|PubMed:22185573}.
|
| Top Pathways |
Peroxisome
|