KIRREL

Gene Symbol KIRREL
Entrez Gene 55243
Alt Symbol NEPH1
Species Human
Gene Type protein-coding
Description kin of IRRE like (Drosophila)
Other Description kin of IRRE-like protein 1|kin of irregular chiasm-like protein 1|nephrin related|nephrin-like protein 1
Swissprots Q9H9N1 Q96J84 Q8TB15 Q5W0F8 Q5XKC6 Q7Z7N8 Q9NVA5 Q7Z696
Accessions EAW52852 EAW52853 EAW52854 EAW52855 Q96J84 AA628934 AK001707 BAA91850 AK022708 BAB14192 AK090554 BAC03476 AK094163 AK096361 AK098412 AK297788 BAG60129 AY017369 AAK00529 AY302131 AAP59845 BC025268 AAH25268 BC051356 AAH51356 BC067097 AAH67097 BC082969 AAH82969 BC109192 AAI09193 BC109193 AAI09194 XM_005245305 XP_005245362 XM_011509716 XP_011508018 NM_001286349 NP_001273278 NM_018240 NP_060710
Function Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Predominantly located at podocyte slit diaphragm.
Tissue Specificity Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli. {ECO:0000269|PubMed:11416156}.

Active human KIRREL protein fragment - ab167748 from Abcam

Category Protein
Prices $465.00
Sizes 100 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab167748 and staining overnight with Coomassie Blue. Protein migrates as 65-70 kDa due to glycosylation.

KIRREL peptide - ab109278 from Abcam

Category Peptide

NEPH1 / KIRREL Antibody Blocking Peptide - LS-E17185 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Kirrel1/NEPH1 Blocking Peptide - NBP1-91309PEP from Novus Biologicals

Category Peptide
Prices $169.00
Sizes 100 µg
Species Human

Human NEPH1 (His Tag) protein - orb179692 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human Cells
Species Human

KIRREL Blocking Peptide - 33R-2959 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KIRREL1 Recombinant Protein - 96-488 from ProSci

Category Protein
Source HEK293 cells
Species Human
The purity of rh KIRREL1 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

KIRREL fusion protein - Ag0638 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

KIRREL fusion protein - Ag0639 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

KIRREL fusion protein - ag15869 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

KIRREL fusion protein - ag17578 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human KIRREL, His-tagged - KIRREL-5225H from Creative Biomart

Category Protein
Source HEK293 Cells
Species Human

Recombinant Human KIRREL, Fc-tagged - KIRREL-323H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Human NEPH1 Recombinant - RKQ96J84 from Reprokine

Category Protein
Prices $160.00, $480.00, $1,950.00
Sizes 20 µg, 100 µg, 500 µg
Source Optimized DNA sequence encoding extracellular domain of NEPH1 (GLN17 - ALA499 ) including a C-terminal His tag was expressed in HEK293 cells.
Species Human

Human KIRREL1 / NEPH1 Protein (His Tag) - 15752-H08H-100 from Sino Biological

Category Protein
Prices $298.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Human

Human Kirrel1 / NEPH1 Protein - KI1-H5225 from ACROBiosystems

Category Protein
Prices $350.00, $1,700.00
Sizes 100 µg, 1 mg (500ug x 2)
Source Human Kirrel1 / NEPH1 Protein (Human Kirrel1, His Tag) Gln 17 - Ala 499 (Accession # AAI09193.1) was produced in human 293 cells (HEK293) at ACROBiosystems.
Species Human

Recombinant Human Kin of IRRE-like protein 1(KIRREL) - CSB-YP856956HU CSB-EP856956HU CSB-BP856956HU CSB-MP856956HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Human KIRREL / NEPH1 / KIRREL1 Protein (Fc Tag) - 15752-H02H-50 from Sino Biological

Category Protein
Source Human Cells
Species Human

Human KIRREL1 protein - orb257642 from Biorbyt

Category Protein
Prices $578.00, $2,559.00
Sizes 100 μg, 1 mg
Species Human

Recombinant Human KIRREL Protein, His-tagged - KIRREL-719H from Creative Biomart

Category Protein
Source HEK293
Species Human

Kirrel1/NEPH1 Protein - NBP1-93446PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

KIRREL-Antibody-Center-Blocking-peptide - BP5761c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KIRREL-Blocking-PeptideC-term - BP19861b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KIRREL Peptide, Human - M34GP08229H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Human KIRREL / NEPH1 / KIRREL1 Protein (Fc Tag) - 15752-H02H from ABclonal

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Human
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