Gene Symbol | STK25 |
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Entrez Gene | 10494 |
Alt Symbol | SOK1, YSK1 |
Species | Human |
Gene Type | protein-coding |
Description | serine/threonine kinase 25 |
Other Description | Ste20, yeast homolog|serine/threonine-protein kinase 25|ste20-like kinase|ste20/oxidant stress response kinase 1|sterile 20/oxidant stress-response kinase 1 |
Swissprots | B7Z9K1 Q15522 Q5BJF1 A8K6Z3 O00506 A8K7D2 |
Accessions | AAY14683 AAY88740 EAW71265 EAW71266 O00506 AK092161 BAG52488 AK125895 AK291808 BAF84497 AK291947 BAF84636 AK297374 BAG59817 AK301214 BAG62789 AK302751 BAG63964 AK303719 BAG64697 AK315966 BAH14337 BC007852 AAH07852 BC015793 AAH15793 BC091505 AAH91505 BT019961 AAV38764 BU541010 CB250694 CR936874 CAI59786 D63780 BAA20420 DA624380 DC353271 DQ893230 ABM84156 DQ896559 ABM87558 HY052981 HY315908 X99325 CAA67700 XM_006712197 XP_006712260 XM_011510493 XP_011508795 XM_011510494 XP_011508796 XM_011510495 XP_011508797 XM_011510496 XP_011508798 NM_001271977 NP_001258906 NM_001271978 NP_001258907 NM_001271979 NP_001258908 NM_001271980 NP_001258909 NM_001282305 NP_001269234 NM_001282306 NP_001269235 NM_001282307 NP_001269236 NM_001282308 NP_001269237 NM_006374 NP_006365 |
Function | Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. {ECO:0000269|PubMed:15037601}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15037601}. Golgi apparatus {ECO:0000269|PubMed:15037601}. Note=Localizes to the Golgi apparatus. |
Tissue Specificity | Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung. |
YSK1 CRISPR/Cas9 KO Plasmid (h) - sc-405405 from Santa Cruz Biotechnology
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YSK1 HDR Plasmid (h) - sc-405405-HDR from Santa Cruz Biotechnology
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YSK1 Double Nickase Plasmid (h) - sc-405405-NIC from Santa Cruz Biotechnology
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YSK1 Double Nickase Plasmid (h2) - sc-405405-NIC-2 from Santa Cruz Biotechnology
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YSK1 CRISPR Activation Plasmid (h) - sc-405405-ACT from Santa Cruz Biotechnology
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YSK1 CRISPR Activation Plasmid (h2) - sc-405405-ACT-2 from Santa Cruz Biotechnology
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YSK1 Lentiviral Activation Particles (h) - sc-405405-LAC from Santa Cruz Biotechnology
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YSK1 Lentiviral Activation Particles (h2) - sc-405405-LAC-2 from Santa Cruz Biotechnology
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YSK1 siRNA (h) - sc-39253 from Santa Cruz Biotechnology
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YSK1 shRNA Plasmid (h) - sc-39253-SH from Santa Cruz Biotechnology
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YSK1 shRNA (h) Lentiviral Particles - sc-39253-V from Santa Cruz Biotechnology
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STK25 RNAi - H00010494-R02 from Novus Biologicals
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MISSION® esiRNA - EHU017631 from Sigma-Aldrich
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MISSION® siRNA - SIHK2156 from Sigma-Aldrich
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MISSION® siRNA - SIHK2157 from Sigma-Aldrich
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MISSION® siRNA - SIHK2158 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20735 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20735 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05316 from Sigma-Aldrich
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STK25 siRNA (Human) - CRH7131 from Cohesion Biosciences
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STK25 - MBS8209321 from MyBioSource
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shRNA set against Human STK25 (NM_006374.3) - SHH419764 from Creative biogene
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shRNA set against Human STK25(NM_006374.3) - SHL034392 from Creative biogene
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STK25 shRNA Plasmid (Human) - CHH7131 from Cohesion Biosciences
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STK25 miRNA 3'UTR clone - MiUTR1H-10008 from Creative biogene
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