| Gene Symbol |
TBC1D25
|
| Entrez Gene |
4943
|
| Alt Symbol |
MG81, OATL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TBC1 domain family, member 25
|
| Other Description |
5SN3 snoRNA|TBC1 domain family member 25|ornithine aminotransferase-like 1
|
| Swissprots |
Q3MII4 Q8TAR9 Q3MII6 Q08AN9
|
| Accessions |
EAW50769 EAW50770 EAW50771 EAW50772 Q3MII6 AB449912 BAH16655 AJ508600 AK293521 BAG57003 AK293875 BAG57264 AK294776 BAG57904 AK297924 BAG60241 AK298884 BAG60997 AK299561 BAG61504 AK316199 BAH14570 BC026050 AAH26050 BC036942 BC041614 BC052609 BC064334 BC082255 BC101817 AAI01818 BC101819 AAI01820 BC125088 AAI25089 BC125089 BC143395 BG328213 BI088539 CA447032 DA087200 L08240 AAA59593 NM_001006113 NM_002536 NP_002527
|
| Function |
Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes. {ECO:0000269|PubMed:21383079}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21383079}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:21383079}. Note=It is dispersed in the cytoplasm under nutrient-rich conditions. Localizes at autophagosomes under cell starving conditions.
|
![Western Blot: OATL1 Overexpression Lysate (Adult Normal) [NBP2-10837] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for OATL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2300_OATL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10837-img0001.jpg)