Gene Symbol | PRSS33 |
---|---|
Entrez Gene | 260429 |
Alt Symbol | EOS |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 33 |
Other Description | serine protease 33|serine protease EOS |
Swissprots | A6NNQ3 Q8NF86 Q8N171 |
Accessions | CAD83828 CAL31934 EAW85469 EAW85470 Q8NF86 AF536382 AAN04055 BC036846 AAH36846 BC062334 AAH62334 XM_011522451 XP_011520753 XM_011522452 XP_011520754 NM_152891 NP_690851 |
Function | Serine protease that has amidolytic activity, cleaving its substrates before Arg residues. {ECO:0000269|PubMed:12795636}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in macrophages. Present in the spleen, small and large intestine, lung and brain (at protein level). Highly expressed in peripheral leukocytes, ovary, retina, spleen and stomach. Moderately expressed in thymus, uterus and platelets, as well as some brain tissues, such as thalamus and fetal brain. {ECO:0000269|PubMed:12795636}. |