Gene Symbol | VSX2 |
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Entrez Gene | 338917 |
Alt Symbol | CHX10, HOX10, MCOP2, MCOPCB3, RET1 |
Species | Human |
Gene Type | protein-coding |
Description | visual system homeobox 2 |
Other Description | ceh-10 homeo domain containing homolog|ceh-10 homeodomain-containing homolog|homeobox protein CHX10 |
Swissprots | A1A4X6 P58304 |
Accessions | AJP06701 AJP06702 AJP06703 AJP06704 AJP06705 AJP06706 AJP06707 AJP06708 EAW81163 EAW81164 P58304 AY336059 AAQ01593 BC128153 AAI28154 XM_011536719 XP_011535021 NM_182894 NP_878314 |
Function | Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate. |
Chx10 CRISPR/Cas9 KO Plasmid (h) - sc-401103 from Santa Cruz Biotechnology
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Chx10 HDR Plasmid (h) - sc-401103-HDR from Santa Cruz Biotechnology
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Chx10 Double Nickase Plasmid (h) - sc-401103-NIC from Santa Cruz Biotechnology
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Chx10 Double Nickase Plasmid (h2) - sc-401103-NIC-2 from Santa Cruz Biotechnology
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Chx10 CRISPR Activation Plasmid (h) - sc-401103-ACT from Santa Cruz Biotechnology
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Chx10 CRISPR Activation Plasmid (h2) - sc-401103-ACT-2 from Santa Cruz Biotechnology
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Chx10 Lentiviral Activation Particles (h) - sc-401103-LAC from Santa Cruz Biotechnology
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Chx10 Lentiviral Activation Particles (h2) - sc-401103-LAC-2 from Santa Cruz Biotechnology
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Chx10 siRNA (h) - sc-38647 from Santa Cruz Biotechnology
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Chx10 shRNA Plasmid (h) - sc-38647-SH from Santa Cruz Biotechnology
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Chx10 shRNA (h) Lentiviral Particles - sc-38647-V from Santa Cruz Biotechnology
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CHX10 RNAi - H00338917-R01 from Novus Biologicals
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MISSION® esiRNA - EHU136771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22750 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22750 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10470 from Sigma-Aldrich
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VSX2 siRNA (Human) - CRJ7264 from Cohesion Biosciences
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VSX2 - MBS8222076 from MyBioSource
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Chx10 CRISPR/Cas9 KO Plasmid (h2) - sc-401103-KO-2 from Santa Cruz Biotechnology
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Chx10 HDR Plasmid (h2) - sc-401103-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human VSX2 (NM_182894.2) - SHH445320 from Creative biogene
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Human VSX2 siRNA - orb277765 from Biorbyt
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VSX2 shRNA Plasmid (Human) - CHJ7264 from Cohesion Biosciences
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VSX2 miRNA 3'UTR clone - MiUTR1H-02157 from Creative biogene
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