Gene Symbol |
TDGF1
|
Entrez Gene |
6997
|
Alt Symbol |
CR, CRGF, CRIPTO
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
teratocarcinoma-derived growth factor 1
|
Other Description |
cripto-1 growth factor|epidermal growth factor-like cripto protein CR1
|
Swissprots |
P13385 Q8TCC1
|
Accessions |
AAA61134 EAW64773 EAW64774 P13385 AK313319 BAG36124 AU125451 BC022393 AAH22393 BC067844 AAH67844 CX755454 CX781482 CX785985 DA941183 EU832709 ACE87041 HQ447777 ADQ32262 X14253 CAA32467 NM_001174136 NP_001167607 NM_003212 NP_003203
|
Function |
Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. {ECO:0000269|PubMed:11909953}.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:18930707}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:18930707}.
|
Tissue Specificity |
Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung. {ECO:0000269|PubMed:18835250}.
|