GCDH

Gene Symbol	GCDH
Entrez Gene	2639
Alt Symbol	ACAD5, GCD
Species	Human
Gene Type	protein-coding
Description	glutaryl-CoA dehydrogenase
Other Description	glutaryl-CoA dehydrogenase, mitochondrial|glutaryl-Coenzyme A dehydrogenase
Swissprots	O14719 A8K2Z2 Q92947
Accessions	AAB51174 AAC52079 AER00473 EAW84324 EAW84325 EAW84326 Q92947 AK098370 AK290407 BAF83096 AK296446 BAG59097 AK298772 BAG60914 AK300841 BAG62492 AK309892 AU135567 BC002579 AAH02579 BM855466 BT006706 AAP35352 DA286320 S77773 AAB34724 U69141 AAB08455 XM_006722721 XP_006722784 XM_011527899 XP_011526201 XM_011527900 XP_011526202 NM_000159 NP_000150 NM_013976 NP_039663 NR_102316 NR_102317
Function	Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. {ECO:0000269|PubMed:17176108, ECO:0000269|PubMed:6423663, ECO:0000269|PubMed:8541831}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Isoform 1 and isoform 2 are expressed in fibroblasts and liver.
Top Pathways	Lysine degradation, Fatty acid degradation, Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GCDH CRISPR/Cas9 KO Plasmid (h) - sc-405887 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH HDR Plasmid (h) - sc-405887-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH Double Nickase Plasmid (h) - sc-405887-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH Double Nickase Plasmid (h2) - sc-405887-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH CRISPR Activation Plasmid (h) - sc-405887-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH CRISPR Activation Plasmid (h2) - sc-405887-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH Lentiviral Activation Particles (h) - sc-405887-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH Lentiviral Activation Particles (h2) - sc-405887-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH siRNA (h) - sc-97542 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCDH shRNA Plasmid (h) - sc-97542-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCDH shRNA (h) Lentiviral Particles - sc-97542-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU000561 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9182 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9182 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03842 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03842

GCDH siRNA (Human) - CRH1754 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GCDH - MBS8219265 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human GCDH (NM_000159.2) - SHH299946 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GCDH(NM_000159.2) - SHH079463 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GCDH(NM_013976.2) - SHH079477 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GCDH(NM_000159.2) - SHH079497 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GCDH(NM_013976.2) - SHH079501 from Creative biogene Category siRNA Species Reactivities Human

GCDH CRISPR/Cas9 KO Plasmid (h2) - sc-405887-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCDH HDR Plasmid (h2) - sc-405887-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human GCDH siRNA - orb262256 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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