Gene Symbol | Cyp27b1 |
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Entrez Gene | 13115 |
Alt Symbol | Cp2b, Cyp1, Cyp27b, Cyp40, P450c1, Pddr, Vdd1, Vddr, VddrI, Vdr |
Species | Mouse |
Gene Type | protein-coding |
Description | cytochrome P450, family 27, subfamily b, polypeptide 1 |
Other Description | 1alpha(OH)ase|25(OH)D 1alpha-hydroxylase|25-OHD-1 alpha-hydroxylase|25-hydroxyvitamin D(3) 1-alpha-hydroxylase|25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial|25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha)|25-hydroxyvitamin D3 1alpha-hydroxylase|P450VD1alpha|VD3 1A hydroxylase|calcidiol 1-monooxygenase|cytochrome P450 subfamily XXVIIB polypeptide 1|cytochrome P450, 27b1|cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase)|cytochrome P450C1 alpha|cytochrome P450VD1-alpha|cytochrome p450 27B1 |
Swissprots | O35084 |
Accessions | AAC05184 AAG44889 AAK15024 EDL24463 O35084 AB006034 BAA22434 BC080697 AAH80697 BM119774 CF168641 XM_006513187 XP_006513250 XM_011243350 XP_011241652 NM_010009 NP_034139 |
Function | Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation. |
Subcellular Location | Mitochondrion membrane. |
Tissue Specificity | Kidney. |
Top Pathways | Tuberculosis, Steroid biosynthesis |
CYP27B1 CRISPR/Cas9 KO Plasmid (m) - sc-419925 from Santa Cruz Biotechnology
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CYP27B1 HDR Plasmid (m) - sc-419925-HDR from Santa Cruz Biotechnology
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CYP27B1 Double Nickase Plasmid (m) - sc-419925-NIC from Santa Cruz Biotechnology
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CYP27B1 Double Nickase Plasmid (m2) - sc-419925-NIC-2 from Santa Cruz Biotechnology
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CYP27B1 CRISPR Activation Plasmid (m) - sc-419925-ACT from Santa Cruz Biotechnology
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CYP27B1 CRISPR Activation Plasmid (m2) - sc-419925-ACT-2 from Santa Cruz Biotechnology
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CYP27B1 Lentiviral Activation Particles (m) - sc-419925-LAC from Santa Cruz Biotechnology
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CYP27B1 Lentiviral Activation Particles (m2) - sc-419925-LAC-2 from Santa Cruz Biotechnology
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CYP27B1 siRNA (m) - sc-60480 from Santa Cruz Biotechnology
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CYP27B1 shRNA Plasmid (m) - sc-60480-SH from Santa Cruz Biotechnology
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CYP27B1 shRNA (m) Lentiviral Particles - sc-60480-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN29503 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29503 from Sigma-Aldrich
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CYP27B1 siRNA (Mouse) - CRM0953 from Cohesion Biosciences
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CYP27B1 - MBS8239118 from MyBioSource
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shRNA set against Mouse CYP27B1 (NM_010009.2) - SHH272985 from Creative biogene
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Mouse CYP27B1 siRNA - orb280429 from Biorbyt
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CYP27B1 shRNA Plasmid (Mouse) - CHM0953 from Cohesion Biosciences
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