LIMS2
| Gene Symbol | LIMS2 |
|---|---|
| Entrez Gene | 55679 |
| Alt Symbol | PINCH-2, PINCH2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | LIM and senescent cell antigen-like domains 2 |
| Other Description | ILK-binding protein|LIM and senescent cell antigen-like-containing domain protein 2|LIM-like protein 2|particularly interesting new Cys-His protein 2 |
| Swissprots | B4DMV1 Q7Z4I8 Q9HA13 F5H6E6 Q7Z4I7 A6NLH0 Q7Z4I2 Q8NFE7 Q7Z4I6 |
| Accessions | AAX93074 EAW95327 EAW95328 EAW95329 EAW95330 EAW95331 EAW95332 EAW95333 EAW95334 EAW95335 EAW95336 Q7Z4I7 AF484961 AAM97589 AF520987 AAM77350 AF527764 AAQ09011 AF527765 AAQ09012 AF527766 AAQ09013 AF527767 AAQ09014 AF527768 AAQ09015 AF527769 AAQ09016 AF527770 AAQ09017 AK000906 BAA91419 AK022470 BAB14047 AK055363 BAG51505 AK091652 AK093692 AK094954 AK095790 AK123014 AK297645 BAG60013 AL512716 CAC21657 BC001370 AAH01370 BC008977 AAH08977 BC065816 AAH65816 BP221000 BX458594 CA439343 DA848179 DA890151 DC356496 DR006887 XM_005263709 XP_005263766 XM_005263710 XP_005263767 XM_006712627 XP_006712690 XM_006712628 XP_006712691 XM_011511453 XP_011509755 XR_922961 NM_001136037 NP_001129509 NM_001161403 NP_001154875 NM_001161404 NP_001154876 NM_001256542 NP_001243471 NM_017980 NP_060450 |
| Function | Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration. {ECO:0000269|PubMed:12167643}. |
| Subcellular Location | Nucleus {ECO:0000305}. Cell junction, focal adhesion {ECO:0000269|PubMed:12167643}. Cell membrane {ECO:0000269|PubMed:12167643}; Peripheral membrane protein {ECO:0000269|PubMed:12167643}; Cytoplasmic side {ECO:0000269|PubMed:12167643}. |
Pinch-2 CRISPR/Cas9 KO Plasmid (h) - sc-407604 from Santa Cruz Biotechnology
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Pinch-2 HDR Plasmid (h) - sc-407604-HDR from Santa Cruz Biotechnology
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Pinch-2 Double Nickase Plasmid (h) - sc-407604-NIC from Santa Cruz Biotechnology
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Pinch-2 Double Nickase Plasmid (h2) - sc-407604-NIC-2 from Santa Cruz Biotechnology
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Pinch-2 CRISPR Activation Plasmid (h) - sc-407604-ACT from Santa Cruz Biotechnology
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Pinch-2 CRISPR Activation Plasmid (h2) - sc-407604-ACT-2 from Santa Cruz Biotechnology
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Pinch-2 Lentiviral Activation Particles (h) - sc-407604-LAC from Santa Cruz Biotechnology
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Pinch-2 Lentiviral Activation Particles (h2) - sc-407604-LAC-2 from Santa Cruz Biotechnology
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Pinch-2 siRNA (h) - sc-106412 from Santa Cruz Biotechnology
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Pinch-2 shRNA Plasmid (h) - sc-106412-SH from Santa Cruz Biotechnology
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Pinch-2 shRNA (h) Lentiviral Particles - sc-106412-V from Santa Cruz Biotechnology
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LIMS2 RNAi - H00055679-R01 from Novus Biologicals
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MISSION® esiRNA - EHU081551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11726 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11726 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07099 from Sigma-Aldrich
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LIMS2 siRNA (Human) - CRJ0827 from Cohesion Biosciences
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shRNA set against Human LIMS2 (NM_017980.4) - SHH330443 from Creative biogene
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Human LIMS2 siRNA - orb271328 from Biorbyt
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LIMS2 shRNA Plasmid (Human) - CHJ0827 from Cohesion Biosciences
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LIMS2 miRNA 3'UTR clone - MiUTR3H-09565 from Creative biogene
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LIMS2 miRNA 3'UTR clone - MiUTR3H-09566 from Creative biogene
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LIMS2 miRNA 3'UTR clone - MiUTR3H-09567 from Creative biogene
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LIMS2 miRNA 3'UTR clone - MiUTR3H-09568 from Creative biogene
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