Gene Symbol | HSPG2 |
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Entrez Gene | 3339 |
Alt Symbol | HSPG, PLC, PRCAN, SJA, SJS, SJS1 |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate proteoglycan 2 |
Other Description | basement membrane-specific heparan sulfate proteoglycan core protein|endorepellin (domain V region)|perlecan proteoglycan |
Swissprots | Q5SZI3 Q16287 P98160 Q9H3V5 |
Accessions | AAB95116 CAC18534 EAW94994 EAW94995 EAW94996 EAW94997 P98160 AA450342 AA507437 AB209851 BAD93088 AF479675 AAL79552 AI131329 AK126516 BC033152 BC109204 AAI09205 BE273742 BG056875 CA407545 CD518822 CX165450 M64283 AAA52699 M85289 AAA52700 S76436 AAB21121 X62515 CAA44373 XM_006710594 XP_006710657 XM_006710595 XP_006710658 XM_006710596 XP_006710659 XM_006710597 XP_006710660 XM_011541317 XP_011539619 XM_011541318 XP_011539620 XM_011541319 XP_011539621 XM_011541320 XP_011539622 XM_011541321 XP_011539623 XM_011541322 XP_011539624 NM_001291860 NP_001278789 NM_005529 NP_005520 |
Function | The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. |
Tissue Specificity | Found in the basement membranes. |
Top Pathways | ECM-receptor interaction, Proteoglycans in cancer |
Perlecan CRISPR/Cas9 KO Plasmid (h) - sc-400823 from Santa Cruz Biotechnology
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Perlecan HDR Plasmid (h) - sc-400823-HDR from Santa Cruz Biotechnology
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Perlecan Double Nickase Plasmid (h) - sc-400823-NIC from Santa Cruz Biotechnology
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Perlecan Double Nickase Plasmid (h2) - sc-400823-NIC-2 from Santa Cruz Biotechnology
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Perlecan CRISPR Activation Plasmid (h) - sc-400823-ACT from Santa Cruz Biotechnology
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Perlecan CRISPR Activation Plasmid (h2) - sc-400823-ACT-2 from Santa Cruz Biotechnology
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Perlecan Lentiviral Activation Particles (h) - sc-400823-LAC from Santa Cruz Biotechnology
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Perlecan Lentiviral Activation Particles (h2) - sc-400823-LAC-2 from Santa Cruz Biotechnology
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Perlecan siRNA (h) - sc-44010 from Santa Cruz Biotechnology
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Perlecan shRNA Plasmid (h) - sc-44010-SH from Santa Cruz Biotechnology
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Perlecan shRNA (h) Lentiviral Particles - sc-44010-V from Santa Cruz Biotechnology
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Heparan Sulfate Proteoglycan 2 RNAi - H00003339-R01 from Novus Biologicals
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MISSION® esiRNA - EHU151431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10384 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10384 from Sigma-Aldrich
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HSPG2 siRNA (Human) - CRH2276 from Cohesion Biosciences
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HSPG2 - MBS8228251 from MyBioSource
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Perlecan CRISPR/Cas9 KO Plasmid (h2) - sc-400823-KO-2 from Santa Cruz Biotechnology
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Perlecan HDR Plasmid (h2) - sc-400823-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human HSPG2 (NM_005529.5) - SHH315797 from Creative biogene
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shRNA set against Human HSPG2(NM_005529.5) - SHH135047 from Creative biogene
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Human HSPG2 siRNA - orb262778 from Biorbyt
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HSPG2 shRNA Plasmid (Human) - CHH2276 from Cohesion Biosciences
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HSPG2 miRNA 3'UTR clone - MiUTR1H-04747 from Creative biogene
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