Gene Symbol | PDE6A |
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Entrez Gene | 5145 |
Alt Symbol | CGPR-A, PDEA, RP43 |
Species | Human |
Gene Type | protein-coding |
Description | phosphodiesterase 6A, cGMP-specific, rod, alpha |
Other Description | GMP-PDE alpha|PDE V-B1|cGMP phosphodiesterase alpha subunit|rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha|rod photoreceptor cGMP phosphodiesterase alpha subunit |
Swissprots | P16499 Q0P638 |
Accessions | AAC33831 EAW61756 EAW61757 P16499 AB593141 BAJ84077 BC035909 AAH35909 BC144044 BU734142 BX537592 BX648986 M26061 AAB69155 XM_011537648 XP_011535950 XM_011537649 XP_011535951 XM_011537650 XP_011535952 XM_011537651 XP_011535953 XM_011537652 XP_011535954 XM_011537653 XP_011535955 XM_011537654 XP_011535956 NM_000440 NP_000431 |
Function | This protein participates in processes of transmission and amplification of the visual signal. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Phototransduction, Purine metabolism |
PDE6Aα CRISPR/Cas9 KO Plasmid (h) - sc-408759 from Santa Cruz Biotechnology
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PDE6Aα HDR Plasmid (h) - sc-408759-HDR from Santa Cruz Biotechnology
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PDE6Aα Double Nickase Plasmid (h) - sc-408759-NIC from Santa Cruz Biotechnology
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PDE6Aα Double Nickase Plasmid (h2) - sc-408759-NIC-2 from Santa Cruz Biotechnology
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PDE6Aα CRISPR Activation Plasmid (h) - sc-408759-ACT from Santa Cruz Biotechnology
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PDE6Aα CRISPR Activation Plasmid (h2) - sc-408759-ACT-2 from Santa Cruz Biotechnology
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PDE6Aα Lentiviral Activation Particles (h) - sc-408759-LAC from Santa Cruz Biotechnology
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PDE6Aα Lentiviral Activation Particles (h2) - sc-408759-LAC-2 from Santa Cruz Biotechnology
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PDE6Aα siRNA (h) - sc-45461 from Santa Cruz Biotechnology
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PDE6Aα shRNA Plasmid (h) - sc-45461-SH from Santa Cruz Biotechnology
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PDE6Aα shRNA (h) Lentiviral Particles - sc-45461-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU034681 from Sigma-Aldrich
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MISSION® esiRNA - EHU102771 from Sigma-Aldrich
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MISSION® esiRNA - EHU036581 from Sigma-Aldrich
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MISSION® esiRNA - EHU104631 from Sigma-Aldrich
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MISSION® esiRNA - EHU104091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1709 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1709 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02425 from Sigma-Aldrich
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PDE6A siRNA (Human) - CRH3425 from Cohesion Biosciences
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shRNA set against Human Pde6a (NM_000440.2) - SHH372500 from Creative biogene
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PDE6A shRNA Plasmid (Human) - CHH3425 from Cohesion Biosciences
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