Gene Symbol | GBP5 |
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Entrez Gene | 115362 |
Alt Symbol | GBP-5 |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 5 |
Other Description | GBP-TA antigen|GTP-binding protein 5|guanine nucleotide-binding protein 5|guanylate-binding protein 5 |
Swissprots | Q96PP8 Q86TM5 B2RCE1 |
Accessions | EAW73141 Q96PP8 AF288815 AAL02055 AF328727 AAO40731 AF430642 AAN39035 AF430643 AAN39036 AK090479 BAC03460 AK315064 BAG37538 AL832285 AY358953 AAQ89312 BC031639 AAH31639 BC033761 AAH33761 CD367361 DQ895650 ABM86576 EU176216 ABW03667 NM_001134486 NP_001127958 NM_052942 NP_443174 |
Function | Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. {ECO:0000269|PubMed:22461501}. |
Subcellular Location | Cytoplasm. Membrane; Lipid-anchor. |
GBP5 CRISPR/Cas9 KO Plasmid (h) - sc-403674 from Santa Cruz Biotechnology
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GBP5 HDR Plasmid (h) - sc-403674-HDR from Santa Cruz Biotechnology
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GBP5 Double Nickase Plasmid (h) - sc-403674-NIC from Santa Cruz Biotechnology
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GBP5 Double Nickase Plasmid (h2) - sc-403674-NIC-2 from Santa Cruz Biotechnology
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GBP5 CRISPR Activation Plasmid (h) - sc-403674-ACT from Santa Cruz Biotechnology
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GBP5 CRISPR Activation Plasmid (h2) - sc-403674-ACT-2 from Santa Cruz Biotechnology
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GBP5 Lentiviral Activation Particles (h) - sc-403674-LAC from Santa Cruz Biotechnology
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GBP5 Lentiviral Activation Particles (h2) - sc-403674-LAC-2 from Santa Cruz Biotechnology
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GBP5 siRNA (h) - sc-88824 from Santa Cruz Biotechnology
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GBP5 shRNA Plasmid (h) - sc-88824-SH from Santa Cruz Biotechnology
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GBP5 shRNA (h) Lentiviral Particles - sc-88824-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9172 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9172 from Sigma-Aldrich
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GBP5 siRNA (Human) - CRJ4446 from Cohesion Biosciences
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GBP5 - MBS8200295 from MyBioSource
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shRNA set against Human GBP5 (NM_052942.3) - SHH299830 from Creative biogene
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Human GBP5 siRNA - orb274947 from Biorbyt
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GBP5 shRNA Plasmid (Human) - CHJ4446 from Cohesion Biosciences
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GBP5 miRNA 3'UTR clone - MiUTR3H-11912 from Creative biogene
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GBP5 miRNA 3'UTR clone - MiUTR3H-11913 from Creative biogene
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